Lab on a chip for continuous-flow magnetic cell separation

M Hejazian, W Li, NT Nguyen - Lab on a Chip, 2015 - pubs.rsc.org
Separation of cells is a key application area of lab-on-a-chip (LOC) devices. Among the
various methods, magnetic separation of cells utilizing microfluidic devices offers the merits …

Fundamentals and application of magnetic particles in cell isolation and enrichment: a review

BD Plouffe, SK Murthy, LH Lewis - Reports on Progress in …, 2014 - iopscience.iop.org
Magnetic sorting using magnetic beads has become a routine methodology for the
separation of key cell populations from biological suspensions. Due to the inherent ability of …

Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers

C D'Souza-Schorey, JW Clancy - Genes & development, 2012 - genesdev.cshlp.org
Recent advances in the study of tumor-derived microvesicles reveal new insights into the
cellular basis of disease progression and the potential to translate this knowledge into …

Microfluidics for cell separation

AAS Bhagat, H Bow, HW Hou, SJ Tan, J Han… - Medical & biological …, 2010 - Springer
The need for efficient cell separation, an essential preparatory step in many biological and
medical assays, has led to the recent development of numerous microscale separation …

[HTML][HTML] Recent advances for cancer detection and treatment by microfluidic technology, review and update

N Bargahi, S Ghasemali, S Jahandar-Lashaki… - Biological Procedures …, 2022 - Springer
Numerous cancer-associated deaths are owing to a lack of effective diagnostic and
therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a …

Microfluidic approaches for cancer cell detection, characterization, and separation

J Chen, J Li, Y Sun - Lab on a Chip, 2012 - pubs.rsc.org
This article reviews the recent developments in microfluidic technologies for in vitro cancer
diagnosis. We summarize the working principles and experimental results of key microfluidic …

Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells

Y Xu, JA Phillips, J Yan, Q Li, ZH Fan… - Analytical chemistry, 2009 - ACS Publications
The ability to diagnose cancer based on the detection of rare cancer cells in blood or other
bodily fluids is a significant challenge. To address this challenge, we have developed a …

Electrokinetic motion of particles and cells in microchannels

Y Kang, D Li - Microfluidics and nanofluidics, 2009 - Springer
This paper provides an overview of the electrokinetic phenomena associated with particles
and cells in microchannel systems. The most important phenomena covered include …

Microfluidics technologies for blood-based cancer liquid biopsies

Y Sun, TA Haglund, AJ Rogers, AF Ghanim… - Analytica chimica …, 2018 - Elsevier
Blood-based liquid biopsies provide a minimally invasive alternative to identify cellular and
molecular signatures that can be used as biomarkers to detect early-stage cancer, predict …

Cell manipulation with magnetic particles toward microfluidic cytometry

C Liu, T Stakenborg, S Peeters, L Lagae - Journal of Applied Physics, 2009 - pubs.aip.org
Magnetic particles have become a promising tool for nearly all major lab-on-a-chip (LOC)
applications, from sample capturing, purification, enrichment, transport to detection. For …