Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

Regulatory roles of six-transmembrane epithelial antigen of the prostate family members in the occurrence and development of malignant tumors

WJ Chen, HT Wu, CL Li, YK Lin, ZX Fang… - Frontiers in Cell and …, 2021 - frontiersin.org
The human six-transmembrane epithelial antigen of the prostate (STEAP) proteins, which
include STEAP1–4 and atypical STEAP1B, contain six transmembrane domains and are …

Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation

D Yan, W Dong, Q He, M Yang, L Huang, J Kong… - …, 2019 - thelancet.com
Background Metastasis is a major obstacle in the treatment of bladder cancer (BC). Circular
RNAs exert various functions in the aggressive biological behaviour of cancers. In this study …

The tumor suppressive roles and prognostic values of STEAP family members in breast cancer

HT Wu, WJ Chen, Y Xu, JX Shen… - BioMed research …, 2020 - Wiley Online Library
Objective. To investigate the expression patterns and prognostic values of STEAP family
members in the occurrence and development of breast cancer. Materials and Methods. The …

Underlying mechanisms of brain aging and neurodegenerative diseases as potential targets for preventive or therapeutic strategies using phytochemicals

HM Abdolmaleky, JR Zhou - Nutrients, 2023 - mdpi.com
During aging, several tissues and biological systems undergo a progressive decline in
function, leading to age-associated diseases such as neurodegenerative, inflammatory …

KRT15 overexpression predicts poor prognosis in colorectal cancer.

X Rao, J Wang, HM Song, B Deng, JG Li - Neoplasma, 2020 - search.ebscohost.com
Abstract Keratin-15 (KRT15) is a type I keratin lacking a defined type II partner and plays a
key role in maintaining cytoplasmic stability. Recently, studies report that KRT15 is …

An insight into the complex roles of metallothioneins in malignant diseases with emphasis on (sub) isoforms/isoforms and epigenetics phenomena

S Krizkova, M Kepinska, G Emri, T Eckschlager… - Pharmacology & …, 2018 - Elsevier
Metallothioneins (MTs) belong to a group of small cysteine-rich proteins that are ubiquitous
throughout all kingdoms. The main function of MTs is scavenging of free radicals and …

Racial disparity in breast cancer: can it be mattered for prognosis and therapy

V Gupta, I Haque, J Chakraborty, S Graff… - Journal of cell …, 2018 - Springer
Breast cancer (BC) has emerged as a deadly disease that affects the lives of millions of
women worldwide. It is the second leading cause of cancer-related deaths in the United …

Alcohol and cancer stem cells

M Xu, J Luo - Cancers, 2017 - mdpi.com
Heavy alcohol consumption has been associated with increased risk of several cancers,
including cancer of the colon, rectum, female breast, oral cavity, pharynx, larynx, liver, and …

NRF2/ACSS2 axis mediates the metabolic effect of alcohol drinking on esophageal squamous cell carcinoma

JO Odera, Z Xiong, C Huang, N Gu, W Yang… - Biochemical …, 2020 - portlandpress.com
Alcohol drinking is a leading risk factor for the development of esophageal squamous cell
carcinoma (ESCC). However, the molecular mechanisms of alcohol-associated ESCC …