Immunomodulatory protein hydrolysate consumption may delay or prevent western immune-
related diseases. In order to purposively develop protein hydrolysates with an optimal and …

Cationic antimicrobial peptides (CAMPs) are critical front line contributors to host defense
against invasive bacterial infection. These immune factors have direct killing activity toward …

Lysozymes are ancient and important components of the innate immune system of animals
that hydrolyze peptidoglycan, the major bacterial cell wall polymer. Bacteria engaging in …

Elafin and secretory leukocyte protease inhibitor (SLPI) are pleiotropic molecules chiefly
synthesized at the mucosal surface that have a fundamental role in the surveillance against …

Group A Streptococcus (GAS; Streptococcus pyogenes) is a human pathogen which causes
significant morbidity and mortality globally. GAS typically infects the throat and skin of the …

Group A streptococci produce a wide variety of secreted extracellular products, many of
which are considered virulence factors. The number of these potential virulence factors …

Epithelial linings serve as physical barriers and produce antimicrobial peptides (AMPs) to
maintain host integrity. Examples are the bactericidal proteins midkine (MK) and …

Since the middle ages, essential oils (EOs) have been widely used for bactericidal, virucidal,
fungicidal, antiparasitical, insecticidal, medicinal and cosmetic applications. Nowadays, it is …

To identify sequences with a role in microbial pathogenesis, we assessed the adequacy of
their annotation by existing controlled vocabularies and sequence databases. Our goal was …

Defensins, as a prominent family of antimicrobial peptides (AMP), are major effectors of the
innate immunity with a broad range of immune modulatory and antimicrobial activities. In …