Hepatocellular carcinoma (HCC) is one of the most lethal tumors in China and worldwide,
although first-line therapies for HCC, such as atezolizumab and bevacizumab, have been …

Immunotherapy has revolutionized the treatment of cancer in recent years and achieved
overall success and long‐term clinical benefit in patients with a wide variety of cancer types …

Diffuse intrinsic pontine glioma (DIPG) is an aggressive brain stem tumor and the leading
cause of pediatric cancer-related death. To date, these tumors remain incurable …

Objective Macrophage-mediated inflammation plays a significant role in the development
and progression of diabetic nephropathy (DN). However, the underlying mechanisms …

Abstract Objectives Interleukin‐6 (IL‐6) is critical for the development of non‐small‐cell lung
cancer (NSCLC). Recently, we identified T‐cell immunoglobulin domain and mucin domain …

Background Emerging evidence suggests that circular RNAs play critical roles in disease
development especially in cancers. Previous genome-wide RNA-seq studies found that a …

Hepatocellular carcinoma (HCC) is one of the most common tumors in the world, and its
mortality is still on the rise. Limited treatments and low chemotherapy sensitivity of HCC …

T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3) expression has been
a trending topic in recent years due to its differential expression in a wide range of …

Context Programmed cell death protein-1 (PD-1), cytotoxic T-lymphocyte antigen 4 (CTLA-
4), T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), lymphocyte activation …

Chemotherapy resistance of breast cancer poses a great challenge to the survival of
patients. During breast cancer treatment, the development of intrinsic and acquired drug …