In recent years, there has been a renewed interest in utilizing antibody fragment
crystallizable (Fc) functions to prevent and control viral infections. The protective and …

Highlights•Host immune responses play both protective and pathogenic roles in IAV and
CoV infections.•Synergy of adaptive and innate immunity is required for efficient control of …

Broadly neutralizing antibodies (Abs) that bind the influenza virus hemagglutinin (HA) stem
may enable universal influenza vaccination. Here, we show that anti-stem Abs sterically …

Influenza B viruses cause seasonal epidemics and are a considerable burden to public
health. However, protection by current seasonal vaccines is suboptimal due to the antigenic …

Vaccination is the best way to prevent influenza virus infections, but the diversity of
antigenically distinct isolates is a persistent challenge for vaccine development. In order to …

The constant emergence of SARS-CoV-2 variants continues to impair the efficacy of existing
neutralizing antibodies, especially XBB. 1.5 and EG. 5, which showed exceptional immune …

Protective Ebola virus (EBOV) antibodies have neutralizing activity and induction of antibody
constant domain (Fc)-mediated innate immune effector functions. Efforts to enhance Fc …

Antibodies capable of neutralizing SARS-CoV-2 are well studied, but Fc receptor–
dependent antibody activities that can also significantly impact the course of infection have …

It is evident that the emergence of infectious diseases, which have the potential for spillover
from animal reservoirs, pose an ongoing threat to global health. Zoonotic transmission …

Simple Summary The high incidence and death rates of breast cancer make the
development of new therapies an urgent need. The introduction into the clinic of the anti …