The immunogenicity of current influenza virus vaccines is assessed by measuring an
increase of influenza virus-specific antibodies in a hemagglutination inhibition assay. This …

Influenza virus is a respiratory pathogen that can cause disease in humans, with symptoms
ranging from mild to life-threatening. The vast majority of influenza virus infections in …

Monoclonal antibodies have become an important class of therapeutics in the last 30 years.
Because the mechanism of action of therapeutic antibodies is intimately linked to their …

Hemagglutinin (HA) is the immunodominant protein of the influenza virus. We previously
showed that mice injected with a monoglycosylated influenza A HA (HAmg) produced cross …

Zika virus is a mosquito-borne flavivirus which can cause severe disease in humans,
including microcephaly and other congenital malformations in newborns and Guillain-Barré …

Highlights•The strain-specificity of most neutralizing antibodies against influenza poses
difficulties in inducing broadly protective immunity.•Influenza-specific ADCC assists in the …

Influenza causes millions of cases of hospitalizations annually and remains a public health
concern on a global scale. Vaccines are developed and have proven to be the most effective …

The neuraminidase (NA) of influenza A and B viruses plays a distinct role in viral replication
and has a highly conserved catalytic site. Numerous sialic (neuraminic) acid analogs that …

In this review, we analyze the epidemiological and ecological features of influenza B, one of
the most common and severe respiratory infections. The review presents various strategies …

Abstract Influenza viruses infect 5–30% of the world's population annually, resulting in
millions of incidents of hospitalization and thousands of mortalities worldwide every year …