[HTML][HTML] Identification of broad-spectrum neutralizing antibodies against influenza A virus and evaluation of their prophylactic efficacy in mice
S Son, SB Ahn, G Kim, Y Jang, C Ko, M Kim, SJ Kim - Antiviral Research, 2023 - Elsevier
Influenza A virus continuously infects humans and the antigenic shifts of this respiratory virus
enable it to cross the species barrier, threatening public health with the risk of pandemics …
enable it to cross the species barrier, threatening public health with the risk of pandemics …
A live-attenuated prime, inactivated boost vaccination strategy with chimeric hemagglutinin-based universal influenza virus vaccines provides protection in ferrets: a …
R Nachbagauer, F Krammer, RA Albrecht - Vaccines, 2018 - mdpi.com
Influenza viruses cause severe diseases and mortality in humans on an annual basis. The
current influenza virus vaccines can confer protection when they are well-matched with the …
current influenza virus vaccines can confer protection when they are well-matched with the …
Antibodies directed toward neuraminidase N1 control disease in a mouse model of influenza
ER Job, M Schotsaert, LI Ibañez, A Smet… - Journal of …, 2018 - Am Soc Microbiol
There is increasing evidence to suggest that antibodies directed toward influenza A virus
(IAV) neuraminidase (NA) are an important correlate of protection against influenza in …
(IAV) neuraminidase (NA) are an important correlate of protection against influenza in …
Broad and protective influenza B virus neuraminidase antibodies in humans after vaccination and their clonal persistence as plasma cells
MS Piepenbrink, A Nogales, M Basu, CF Fucile… - MBio, 2019 - Am Soc Microbiol
Although most seasonal inactivated influenza vaccines (IIV) contain neuraminidase (NA),
the extent and mechanisms of action of protective human NA-specific humoral responses …
the extent and mechanisms of action of protective human NA-specific humoral responses …
Strategies to induce broadly protective antibody responses to viral glycoproteins
F Krammer - Expert Review of Vaccines, 2017 - Taylor & Francis
Introduction: Currently, several universal/broadly protective influenza virus vaccine
candidates are under development. Many of these vaccines are based on strategies to …
candidates are under development. Many of these vaccines are based on strategies to …
Flu-COVID combo recombinant protein vaccines elicited protective immune responses against both influenza and SARS-CoV-2 viruses infection
SARS-CoV-2 and Influenza viruses are both highly transmissible airborne viruses and
causing high morbidity and mortality. Co-infection of these two viruses results in severe …
causing high morbidity and mortality. Co-infection of these two viruses results in severe …
In Vivo Imaging of Influenza Virus Infection in Immunized Mice
R Czakó, L Vogel, EW Lamirande, KW Bock, IN Moore… - MBio, 2017 - Am Soc Microbiol
Immunization is the cornerstone of seasonal influenza control and represents an important
component of pandemic preparedness strategies. Using a bioluminescent reporter virus, we …
component of pandemic preparedness strategies. Using a bioluminescent reporter virus, we …
Characterization of hemagglutinin antigens on influenza virus and within vaccines using electron microscopy
JR Gallagher, DM McCraw, U Torian, NM Gulati… - Vaccines, 2018 - mdpi.com
Influenza viruses affect millions of people worldwide on an annual basis. Although vaccines
are available, influenza still causes significant human mortality and morbidity. Vaccines …
are available, influenza still causes significant human mortality and morbidity. Vaccines …
Challenges for the newborn immune response to respiratory virus infection and vaccination
KF Crofts, MA Alexander-Miller - Vaccines, 2020 - mdpi.com
The initial months of life reflect an extremely challenging time for newborns as a naïve
immune system is bombarded with a large array of pathogens, commensals, and other …
immune system is bombarded with a large array of pathogens, commensals, and other …
Hemagglutinin stalk-binding antibodies enhance effectiveness of neuraminidase inhibitors against influenza via Fc-dependent effector functions
The conserved hemagglutinin stalk domain is an attractive target for broadly effective
antibody-based therapeutics and next-generation universal influenza vaccines. Protection …
antibody-based therapeutics and next-generation universal influenza vaccines. Protection …