Induction of cross-clade antibody and T-cell responses by a modified vaccinia virus Ankara–Based influenza A (H5N1) vaccine in a randomized phase 1/2a clinical …

RD de Vries, AF Altenburg… - The Journal of …, 2018 - academic.oup.com
Background High-pathogenicity avian influenza viruses continue to circulate in poultry and
wild birds and occasionally infect humans, sometimes with fatal outcomes. Development of …

The potential role of Fc-receptor functions in the development of a universal influenza vaccine

S Jegaskanda - Vaccines, 2018 - mdpi.com
Despite global vaccination efforts, influenza virus continues to cause yearly epidemics and
periodic pandemics throughout most of the world. Many of us consider the generation of …

Poly-γ-glutamic acid complexed with alum induces cross-protective immunity of pandemic H1N1 vaccine

QT Nguyen, C Kwak, WS Lee, J Kim, J Jeong… - Frontiers in …, 2019 - frontiersin.org
The use of a good vaccine adjuvant may induce a higher immunogenicity profile of vaccine
antigens. Here, we developed a new adjuvant by combining poly-γ-glutamic acid (γ-PGA) …

Immunological responses to influenza vaccination: lessons for improving vaccine efficacy

TT Wang, S Bournazos, JV Ravetch - Current opinion in immunology, 2018 - Elsevier
Highlights•IgG immune complexes are generated upon influenza vaccination.•Interactions of
the IgG Fc domain with FcγRs induce immunomodulatory functions.•Influenza vaccine …

Zwitter-repel: An anti-fouling coating promoting electrochemical biosensing in biological fluids

S Saxena, Y Lu, Z Zhang, Y Li, L Soleymani… - Chemical Engineering …, 2024 - Elsevier
Most electrochemical biosensors require sample processing to reduce biofouling induced by
the complex composition of biological samples that typically causes a decrease in the target …

[HTML][HTML] Understanding the treatment benefit of hyperimmune anti-influenza intravenous immunoglobulin (Flu-IVIG) for severe human influenza

HA Vanderven, DN Wentworth, WM Han, H Peck… - JCI insight, 2023 - ncbi.nlm.nih.gov
BACKGROUND Antibody-based therapies for respiratory viruses are of increasing
importance. The INSIGHT 006 trial administered anti-influenza hyperimmune intravenous …

Challenges for the newborn following influenza virus infection and prospects for an effective vaccine

MA Alexander-Miller - Frontiers in immunology, 2020 - frontiersin.org
Newborns are at significantly increased risk of severe disease following infection with
influenza virus. This is the collective result of their naïve status, altered immune …

Verdinexor targeting of CRM1 is a promising therapeutic approach against RSV and influenza viruses

JA Pickens, RA Tripp - Viruses, 2018 - mdpi.com
Two primary causes of respiratory tract infections are respiratory syncytial virus (RSV) and
influenza viruses, both of which remain major public health concerns. There are a limited …

Epitope mapping by phage display

GMSG Moreira, V Fühner, M Hust - Phage Display: Methods and Protocols, 2018 - Springer
Among the molecules of the immune system, antibodies, particularly monoclonal antibodies
(mAbs), have been shown to be interesting for many biological applications. Due to their …

[图书][B] Viral pandemics: from smallpox to Covid-19

RE Kavey, A Kavey - 2020 - taylorfrancis.com
Written by a public health practitioner and a medical historian, Viral Pandemics explores the
terrifying world of viruses as the cause of all acute pandemics since 1900, including the …