[HTML][HTML] Looking into endoplasmic reticulum stress: the key to drug-resistance of multiple myeloma?
G Wang, F Fan, C Sun, Y Hu - Cancers, 2022 - mdpi.com
Simple Summary Advances in treatment, especially with novel drugs, have dramatically
improved the survival of multiple myeloma (MM) patients recently. However, frequent …
improved the survival of multiple myeloma (MM) patients recently. However, frequent …
[HTML][HTML] Current approach and novel perspectives in nasopharyngeal carcinoma: the role of targeting proteasome dysregulation as a molecular landmark in …
R Yarza, M Bover, MT Agulló-Ortuño… - Journal of Experimental …, 2021 - Springer
Nasopharyngeal carcinoma (NPC) represents a molecularly paradigmatic tumor given the
complex diversity of environmental as well as host dependent factors that are closely …
complex diversity of environmental as well as host dependent factors that are closely …
[HTML][HTML] Multiple myeloma hinders erythropoiesis and causes anaemia owing to high levels of CCL3 in the bone marrow microenvironment
L Liu, Z Yu, H Cheng, X Mao, W Sui, S Deng, X Wei… - Scientific Reports, 2020 - nature.com
Anaemia is the most common complication of myeloma and is associated with worse clinical
outcomes. Although marrow replacement with myeloma cells is widely considered a …
outcomes. Although marrow replacement with myeloma cells is widely considered a …
[HTML][HTML] Single-cell analysis of multiple myelomas refines the molecular features of bortezomib treatment responsiveness
Both the tumor and tumor microenvironment (TME) are crucial for pathogenesis and
chemotherapy resistance in multiple myeloma (MM). Bortezomib, commonly used for MM …
chemotherapy resistance in multiple myeloma (MM). Bortezomib, commonly used for MM …
Controllable hydrogen release for gas-assisted chemotherapy and ultrasonic imaging of drug-resistant tumors
Y Wang, Y Liu, J Zhou, L Lin, C Jia, J Wang… - Chemical Engineering …, 2021 - Elsevier
Gas-assisted therapy and diagnosis of tumors have attracted extensive interest due to their
low toxicity and convenience, but are severely limited by the uncontrollable gas release. In …
low toxicity and convenience, but are severely limited by the uncontrollable gas release. In …
[HTML][HTML] The evidence that 25 (OH) D3 and VK2 MK-7 vitamins influence the proliferative potential and gene expression profiles of multiple myeloma cells and the …
K Łuczkowska, P Kulig, B Baumert, B Machaliński - Nutrients, 2022 - mdpi.com
Multiple myeloma (MM) remains an incurable hematological malignancy. Bortezomib (BTZ)
is a proteasome inhibitor widely used in MM therapy whose potent activity is often hampered …
is a proteasome inhibitor widely used in MM therapy whose potent activity is often hampered …
[HTML][HTML] A drug repurposing strategy for overcoming human multiple myeloma resistance to standard-of-care treatment
K Chroma, Z Skrott, J Gursky, J Bacovsky… - Cell Death & …, 2022 - nature.com
Despite several approved therapeutic modalities, multiple myeloma (MM) remains an
incurable blood malignancy and only a small fraction of patients achieves prolonged …
incurable blood malignancy and only a small fraction of patients achieves prolonged …
Research progress in proteasome inhibitor resistance to multiple myeloma.
J Wu, J Liu - Zhong nan da xue xue bao. Yi xue ban= Journal of …, 2021 - europepmc.org
多发性骨髓瘤 (multiple myeloma, MM) 是一种高度异质性恶性浆细胞疾病. 蛋白酶体抑制剂
(proteasome inhibitors, PIs) 是治疗 MM 的一线药物, 硼替佐米, 伊莎佐米和卡非佐米也广泛 …
(proteasome inhibitors, PIs) 是治疗 MM 的一线药物, 硼替佐米, 伊莎佐米和卡非佐米也广泛 …
[PDF][PDF] Endoplasmic reticulum stress and proteasome inhibitors in multiple myeloma: room for improvement
In the last 2 decades, we witnessed unprecedented progress in multiple myeloma research.
The median survival times doubled, and with the introduction of subsequent new …
The median survival times doubled, and with the introduction of subsequent new …
[HTML][HTML] 蛋白酶体抑制剂在多发性骨髓瘤中耐药的研究进展
吴姣, 刘竞 - Journal of Central South University Medical Sciences, 2021 - ncbi.nlm.nih.gov
多发性骨髓瘤(multiple myeloma, MM) 是一种高度异质性恶性浆细胞疾病。 蛋白酶体抑制剂(
proteasome inhibitors, PIs) 是治疗MM 的一线药物, 硼替佐米、 伊莎佐米和卡非佐米也广泛 …
proteasome inhibitors, PIs) 是治疗MM 的一线药物, 硼替佐米、 伊莎佐米和卡非佐米也广泛 …