Major depressive disorder (MDD or depression) is a debilitating neuropsychiatric syndrome
with genetic, epigenetic, and environmental contributions. Depression is one of the largest …

Post‐stroke depression, a common complication after stroke, severely affects the recovery
and quality of life of patients with stroke. Owing to its complex mechanisms, post‐stroke …

The GPR139 receptor is an orphan G-protein-coupled receptor (GPCR) mainly found in the
central nervous system and is a potential therapeutic target for the treatment of …

Partial agonist activity at the dopamine D2 receptor (D2R) is the primary pharmacological
feature of the third-generation antipsychotics─ aripiprazole, brexpiprazole, and cariprazine …

Rationale Beneficial effects of aripiprazole on cognition in schizophrenia have been
previously reported, but not in recent onset schizophrenia. Cognitive impairments have also …

Deficits in astrocyte function contribute to major depressive disorder (MDD) and suicide, but
the therapeutic effect of directly reactivating astrocytes for depression remains unclear. Here …

Depression, anxiety, and schizophrenia may coexist in psychiatric patients. Moreover, these
disorders are very often associated with cognitive impairments. However, pharmacotherapy …

Background Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD)
comorbidity occurs through exposure to trauma with genetic susceptibility. Neuropeptide-Y …

Background Depression is a chronic psychiatric disorder related to diminished
dopaminergic neurotransmission. Deep brain stimulation (DBS) has shown effectiveness in …

目的探讨帕利哌酮缓释片, 阿立哌唑联合治疗对精神分裂症精神病性症状和认知功能的改善作用
及对催乳素的影响. 方法2019 年9 月—2021 年9 月建德市第四人民医院招募精神分裂症患者96 …