[HTML][HTML] Age-related neuroinflammation and changes in AKT-GSK-3β and WNT/β-CATENIN signaling in rat hippocampus

AMM Orellana, AR Vasconcelos, JA Leite… - Aging (Albany …, 2015 - ncbi.nlm.nih.gov
Aging is a multifactorial process associated with an increased susceptibility to
neurodegenerative disorders which can be related to chronic inflammation. Chronic …

The role of NF-κB inhibitors in cell response to radiation

S Molavi Pordanjani… - Current medicinal …, 2016 - ingentaconnect.com
It is well documented that ionizing radiation (IR) activates the transcription factor (NF-κB)
which is a trigger for resistance cancer cells to treatment. It is involved in activation of pro …

Transcriptional Factor NF‐κB as a Target for Therapy in Parkinson′s Disease

PM Flood, L Qian, LJ Peterson, F Zhang… - Parkinson's …, 2011 - Wiley Online Library
Parkinson′ s disease (PD) is a neurodegenerative condition characterized by chronic
inflammation. Nuclear factor κB (NF‐κB) is a family of inducible transcription factors that are …

Is nucleoredoxin a master regulator of cellular redox homeostasis? its implication in different pathologies

OG Idelfonso-García, BR Alarcón-Sánchez… - Antioxidants, 2022 - mdpi.com
Nucleoredoxin (NXN), an oxidoreductase enzyme, contributes to cellular redox homeostasis
by regulating different signaling pathways in a redox-dependent manner. By interacting with …

Significance of Polymorphism and Expression of miR-146a and NFkB1 Genetic Variants in Patients with Rheumatoid Arthritis

K Bogunia-Kubik, B Wysoczańska, D Piątek… - Archivum immunologiae …, 2016 - Springer
Abstract MicroRNA-146a (miR-146a) has been shown to play an important role in the
regulation of inflammatory innate immune responses, and found to be differentially …

Pyrethroid insecticide lambda-cyhalothrin induces hepatic cytochrome P450 enzymes, oxidative stress and apoptosis in rats

MA Martínez, I Ares, JL Rodríguez, M Martínez… - Science of the total …, 2018 - Elsevier
This study aimed to examine in rats the effects of the Type II pyrethroid lambda-cyhalothrin
on hepatic microsomal cytochrome P450 (CYP) isoform activities, oxidative stress markers …

[HTML][HTML] Phenolic compounds from Chaenomeles speciosa alleviate inflammation in lipopolysaccharide-treated RAW264. 7 macrophages via the NF-κB and MAPK …

F Hu, C Liu, F Wang, C Zhou, M Zhu… - Food Science and …, 2023 - Elsevier
Abstract Chaenomeles speciosa (Sweet) Nakai cultivated widely in temperate regions
possesses anti-inflammatory properties, however, the underlying molecular mechanisms …

Lipid Peroxidation‐Mediated Inflammation Promotes Cell Apoptosis through Activation of NF‐κB Pathway in Rheumatoid Arthritis Synovial Cells

G Yin, Y Wang, X Cen, M Yang… - Mediators of …, 2015 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic
inflammation of multiple joints. The central pathogenesis of RA is the proliferation of synovial …

Potential molecular biomarkers of vestibular schwannoma growth: progress and prospects

Y Zhang, J Long, J Ren, X Huang, P Zhong… - Frontiers in …, 2021 - frontiersin.org
Vestibular schwannomas (VSs, also known as acoustic neuromas) are relatively rare benign
brain tumors stem from the Schwann cells of the eighth cranial nerve. Tumor growth is the …

New highlights on the health-improving effects of sulforaphane

A Briones-Herrera, D Eugenio-Pérez… - Food & function, 2018 - pubs.rsc.org
In this paper, we review recent evidence about the beneficial effects of sulforaphane (SFN),
which is the most studied member of isothiocyanates, on both in vivo and in vitro models of …