Pathophysiology, diagnosis, and management of the no-reflow phenomenon

J Allencherril, H Jneid, D Atar, M Alam, G Levine… - … Drugs and Therapy, 2019 - Springer
Successful reperfusion of an infarct-related coronary artery by primary percutaneous
intervention or fibrinolysis during acute ST-elevation myocardial infarction (STEMI) does not …

Mechanisms of the “no-reflow” phenomenon after acute myocardial infarction: Potential role of pericytes

S Kaul, C Methner, Z Cao, A Mishra - Basic to Translational Science, 2023 - jacc.org
Pericytes contract during myocardial ischemia resulting in capillary constriction and no
reflow. Reversing pericyte contraction pharmacologically reduces no reflow and infarct size …

Mechanism and potential treatment of the “no reflow” phenomenon after acute myocardial infarction: role of pericytes and GPR39

C Methner, Z Cao, A Mishra… - American Journal of …, 2021 - journals.physiology.org
The “no reflow” phenomenon, where the coronary artery is patent after treatment of acute
myocardial infarction (AMI) but tissue perfusion is not restored, is associated with worse …

CHA2DS2-VASc Score is a Predictor of No-Reflow in Patients With ST-Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Intervention

G Ipek, T Onuk, MB Karatas, B Gungor, A Osken… - …, 2016 - journals.sagepub.com
Thrombosis and distal embolization play crucial role in the etiology of no-reflow. CHA2DS2-
VASc score is used to estimate the risk of thromboembolism in patients with atrial fibrillation …

Usefulness of the C‐reactive protein/albumin ratio for predicting no‐reflow in ST‐elevation myocardial infarction treated with primary percutaneous coronary …

Y Karabağ, M Çağdaş, I Rencuzogullari… - European journal of …, 2018 - Wiley Online Library
Background The ratio of serum C‐reactive protein (CRP) to albumin has been proven to be
a more accurate indicator than albumin and CRP levels alone in determining the prognosis …

Clinical and procedural predictors and short-term survival of the patients with no reflow phenomenon after primary percutaneous coronary intervention

T Ashraf, MN Khan, SM Afaque, KF Aamir… - International journal of …, 2019 - Elsevier
Objectives In the present study, we analysed the incidence of no-reflow phenomenon, its
clinical and procedural predictors, and associated in-hospital outcomes for the patients …

The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity

VP Viswanadha, V Dhivya, NM Beeraka… - European Journal of …, 2020 - Elsevier
Myocardial infarction (MI) eventually exacerbates inflammatory response due to the release
of inflammatory and pro-inflammatory factors. The aim of this study is to explore the …

[HTML][HTML] Assessment and treatment for coronary microvascular dysfunction by contrast enhanced ultrasound

J Zhan, L Zhong, J Wu - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
With growing evidence in clinical practice, the understanding of coronary syndromes has
gradually evolved out of focusing on the well-established link between stenosis of epicardial …

Platelet-specific p38α deficiency improved cardiac function after myocardial infarction in mice

P Shi, L Zhang, M Zhang, W Yang, K Wang… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—MAPKs (mitogen-activated protein kinases), especially p38, play detrimental
roles in cardiac diseases and cardiac remodeling post-myocardial infarction. However, the …

[HTML][HTML] Lipid nitroalkene nanoparticles for the focal treatment of ischemia reperfusion

ZY Gary, T Ramasamy, M Fazzari, X Chen… - …, 2022 - ncbi.nlm.nih.gov
Rationale: The treatment of microvascular obstruction (MVO) using ultrasound-targeted LNP
cavitation (UTC) therapy mechanically relieves the physical obstruction in the …