[HTML][HTML] The semantics of microglia activation: neuroinflammation, homeostasis, and stress

SC Woodburn, JL Bollinger, ES Wohleb - Journal of neuroinflammation, 2021 - Springer
Microglia are emerging as critical regulators of neuronal function and behavior in nearly
every area of neuroscience. Initial reports focused on classical immune functions of …

[HTML][HTML] Microglia: Immune and non-immune functions

K Borst, AA Dumas, M Prinz - Immunity, 2021 - cell.com
As resident macrophages of the central nervous system (CNS), microglia are associated
with diverse functions essential to the developing and adult brain during homeostasis and …

Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Cognitive impairment and altered cerebral glucose metabolism in the subacute stage of COVID-19

JA Hosp, A Dressing, G Blazhenets, T Bormann, A Rau… - Brain, 2021 - academic.oup.com
During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic,
neurological symptoms increasingly moved into the focus of interest. In this prospective …

Microglia and central nervous system–associated macrophages—from origin to disease modulation

M Prinz, T Masuda, MA Wheeler… - Annual review of …, 2021 - annualreviews.org
The immune system of the central nervous system (CNS) consists primarily of innate
immune cells. These are highly specialized macrophages found either in the parenchyma …

The blood–brain barrier and blood–tumour barrier in brain tumours and metastases

CD Arvanitis, GB Ferraro, RK Jain - Nature Reviews Cancer, 2020 - nature.com
For a blood-borne cancer therapeutic agent to be effective, it must cross the blood vessel
wall to reach cancer cells in adequate quantities, and it must overcome the resistance …

[HTML][HTML] Blood-brain barrier: from physiology to disease and back

MD Sweeney, Z Zhao, A Montagne… - Physiological …, 2018 - journals.physiology.org
The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

[HTML][HTML] Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's …

X Wang, G Sun, T Feng, J Zhang, X Huang, T Wang… - Cell research, 2019 - nature.com
Recently, increasing evidence has suggested the association between gut dysbiosis and
Alzheimer's disease (AD) progression, yet the role of gut microbiota in AD pathogenesis …

[HTML][HTML] Blood-brain barrier disruption by lipopolysaccharide and sepsis-associated encephalopathy

X Peng, Z Luo, S He, L Zhang, Y Li - Frontiers in cellular and infection …, 2021 - frontiersin.org
As a complex multicellular structure of the vascular system at the central nervous system
(CNS), the blood-brain barrier (BBB) separates the CNS from the system circulation and …

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance

L Akkari, RL Bowman, J Tessier, F Klemm… - Science translational …, 2020 - science.org
Tumor-associated macrophages (TAMs) and microglia (MG) are potent regulators of glioma
development and progression. However, the dynamic alterations of distinct TAM populations …