Hepatitis C virus (HCV) infection is the major risk factor for liver cirrhosis and hepatocellular
carcinoma (HCC). The mechanisms of HCC initiation, growth, and metastasis appear to be …

During most viral infections, the immediate host response is characterized by an induction of
type I IFN. These cytokines have various biological activities, including anti‐viral, anti …

Background. Chronic hepatitis C virus (HCV) infection is a global health problem, resulting
in liver failure, hepatocellular carcinoma, and liver-related death. Natural killer (NK) cells are …

Antitumor T cells are subject to multiple mechanisms of negative regulation,,. Recent
findings that innate lymphoid cells (ILCs) regulate adaptive T cell responses,, led us to …

Hepatitis B virus (HBV) and hepatitis C virus (HCV) cause a large proportion of acute and
chronic liver disease worldwide. Over the past decades many immunological studies …

Since its discovery in the early 1990s, the Janus kinase (JAK)-signal transducer and
activator of transcription (STAT) signaling pathway has been found to play key roles in …

There are 257 million persons worldwide with chronic hepatitis B virus (HBV) infection, a
leading causes of liver cancer. Almost all adults with acute HBV infection have a rapid …

BACKGROUND & AIMS: We studied the functions of natural killer (NK) cells and the role of
the NK cell inhibitory receptor (NKG2A) during hepatitis B virus (HBV) infection in patients …

Natural killer (NK) cells are important mediators of the immune response against microbial
pathogens and tumors. There is growing evidence from mouse and human studies that, NK …

The liver lymphocyte population is enriched with natural killer (NK) cells, which play a key
role in host defense against viral infection and tumor transformation. Recent evidence from …