The biology of progesterone receptor in the normal mammary gland and in breast cancer
AE Obr, DP Edwards - Molecular and cellular endocrinology, 2012 - Elsevier
This paper reviews work on progesterone and the progesterone receptor (PR) in the mouse
mammary gland that has been used extensively as an experimental model. Studies have led …
mammary gland that has been used extensively as an experimental model. Studies have led …
Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration
AF De Nicola, F Labombarda, MCG Deniselle… - Frontiers in …, 2009 - Elsevier
Studies on the neuroprotective and promyelinating effects of progesterone in the nervous
system are of great interest due to their potential clinical connotations. In peripheral …
system are of great interest due to their potential clinical connotations. In peripheral …
[HTML][HTML] Selective progesterone receptor modulators in reproductive medicine: pharmacology, clinical efficacy and safety
P Bouchard, N Chabbert-Buffet, BCJM Fauser - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To discuss the mechanism of action of selective progesterone receptor
modulators (SPRMs) and summarize the preclinical and clinical efficacy and safety data …
modulators (SPRMs) and summarize the preclinical and clinical efficacy and safety data …
The expression and ovarian steroid regulation of endometrial micro-RNAs
T Toloubeydokhti, Q Pan, X Luo, O Bukulmez… - Reproductive …, 2008 - Springer
MicroRNAs (miRNAs) which regulate gene expression stability displayed an aberrant
expression profile in ectopic endometrium (ECE) as compared to eutopic (EUE) and normal …
expression profile in ectopic endometrium (ECE) as compared to eutopic (EUE) and normal …
[HTML][HTML] Mechanism of action of ulipristal acetate for emergency contraception: a systematic review
E Rosato, M Farris, C Bastianelli - Frontiers in pharmacology, 2016 - frontiersin.org
Ulipristal acetate (UPA) is now recommended as first choice hormonal emergency
contraception (EC), due to its higher efficacy and similar safety compared to Levonorgestrel …
contraception (EC), due to its higher efficacy and similar safety compared to Levonorgestrel …
Progesterone‐mediated angiogenic activity of endothelial progenitor cell and angiogenesis in traumatic brain injury rats were antagonized by progesterone receptor …
P Yu, S Li, Z Zhang, X Wen, W Quan, Q Tian… - Cell …, 2017 - Wiley Online Library
Objectives Progesterone (P4) has the potential therapeutic effects for traumatic brain injury
(TBI) whose recovery depended on the enhanced angiogenesis. Endothelial progenitor cell …
(TBI) whose recovery depended on the enhanced angiogenesis. Endothelial progenitor cell …
[HTML][HTML] Biological and clinical impact of imbalanced progesterone receptor isoform ratios in breast cancer
CA Lamb, VT Fabris, BM Jacobsen… - Endocrine-related …, 2018 - erc.bioscientifica.com
There is a consensus that progestins and thus their cognate receptor molecules, the
progesterone receptors (PRs), are essential in the development of the adult mammary gland …
progesterone receptors (PRs), are essential in the development of the adult mammary gland …
[HTML][HTML] Next step in the development of mesoprogestins: the preclinical profile of EC313
K Błaszczak-Świątkiewicz, A Krupa, E Mnich… - Frontiers in …, 2023 - frontiersin.org
Introduction The pharmacological target for progesterone, different progestins, and Selective
Progesterone Receptor Modulators (SPRMs) is the nuclear progesterone receptor (PR) …
Progesterone Receptor Modulators (SPRMs) is the nuclear progesterone receptor (PR) …
Does ulipristal acetate emergency contraception (ella®) interfere with implantation?
HWR Li, M Resche-Rigon, IC Bagchi… - Contraception, 2019 - Elsevier
Background Ulipristal acetate (UPA) 30 mg (ella®, HRA-Pharma, Paris, France) acts as an
emergency contraceptive (EC) by delaying ovulation. Because it is a selective progesterone …
emergency contraceptive (EC) by delaying ovulation. Because it is a selective progesterone …
Progesterone antagonists such as CDB-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer, etc
JS Podolski - US Patent 8,735,381, 2014 - Google Patents
The present invention relates to methods of administering compositions comprising a
progesterone receptor antagonist for use in treating estrogen-dependent conditions. The …
progesterone receptor antagonist for use in treating estrogen-dependent conditions. The …