[HTML][HTML] Pericytes, an overlooked player in vascular pathobiology
D Ferland-McCollough, S Slater, J Richard… - Pharmacology & …, 2017 - Elsevier
Pericytes are a heterogeneous population of cells located in the blood vessel wall. They
were first identified in the 19th century by Rouget, however their biological role and potential …
were first identified in the 19th century by Rouget, however their biological role and potential …
[HTML][HTML] Blood-brain barrier transport machineries and targeted therapy of brain diseases
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Introduction: Desired clinical outcome of pharmacotherapy of brain diseases largely …
Introduction: Desired clinical outcome of pharmacotherapy of brain diseases largely …
Lipid-based nanoformulations in the treatment of neurological disorders
The neurological disorders affect millions of people worldwide, and are bracketed as the
foremost basis of disability-adjusted life years (DALYs). The treatment options are …
foremost basis of disability-adjusted life years (DALYs). The treatment options are …
Hybrid polymer-grafted graphene scaffolds for microvascular tissue engineering and regeneration
The function and organs/tissue and the success of tissue engineering fully depend on the
function of blood vessels and the microvascular system. To regenerate autologous vascular …
function of blood vessels and the microvascular system. To regenerate autologous vascular …
[HTML][HTML] Advanced drug delivery and targeting technologies for the ocular diseases
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Introduction: Ocular targeted therapy has enormously been advanced by implementation of …
Introduction: Ocular targeted therapy has enormously been advanced by implementation of …
Impacts of oxidants and antioxidants on the emergence and progression of Alzheimer's disease
The brain shows a high sensitivity to oxidative stress (OS). Thus, the maintenance and
homeostasis of the brain, in particular neural cells, regarding the reduction-oxidation (redox) …
homeostasis of the brain, in particular neural cells, regarding the reduction-oxidation (redox) …
The current status of immune checkpoint inhibitors in neuro-oncology: a systematic review
CG Brahm, ME van Linde, RH Enting, M Schuur… - Cancers, 2020 - mdpi.com
The introduction of immune checkpoint inhibitors (ICI), as a novel treatment modality, has
transformed the field of oncology with unprecedented successes. However, the efficacy of …
transformed the field of oncology with unprecedented successes. However, the efficacy of …
Application of glycosylation in targeted drug delivery
F Chen, G Huang - European Journal of Medicinal Chemistry, 2019 - Elsevier
Sugar, as a carrier of human energy and an important bioinformatics molecule, plays a vital
role in many important physiological processes, and can control the transmission of …
role in many important physiological processes, and can control the transmission of …
Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat
Background Notwithstanding increasing knowledge of titanium dioxide nanoparticles (TiO 2
NPs) passing through biological barriers, their biodistribution to the central nervous system …
NPs) passing through biological barriers, their biodistribution to the central nervous system …
Peptide-mediated drug delivery across the blood-brain barrier for targeting brain tumors
Introduction: Transportation of the nutrients and other substances from the blood to the brain
is selectively controlled by the brain capillary endothelial cells that form a restrictive barrier …
is selectively controlled by the brain capillary endothelial cells that form a restrictive barrier …