Obesity and the risk of cardiometabolic diseases

PL Valenzuela, P Carrera-Bastos… - Nature reviews …, 2023 - nature.com
The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

[HTML][HTML] Adiponectin: Structure, physiological functions, role in diseases, and effects of nutrition

K Khoramipour, K Chamari, AA Hekmatikar, A Ziyaiyan… - Nutrients, 2021 - mdpi.com
Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …

Perivascular adipose tissue inflammation in vascular disease

R Nosalski, TJ Guzik - British journal of pharmacology, 2017 - Wiley Online Library
Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of
cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in …

Weight loss, improved physical performance, cognitive function, eating behavior, and metabolic profile in a 12-week ketogenic diet in obese adults

N Mohorko, M Černelič-Bizjak, T Poklar-Vatovec… - Nutrition research, 2019 - Elsevier
The ketogenic diet (KD) is being increasingly promoted as a strategy to fight obesity.
Although the KD is effective for weight loss and weight control, comprehensive …

The role of epicardial adipose tissue in cardiac biology: classic concepts and emerging roles

AS Antonopoulos, C Antoniades - The Journal of physiology, 2017 - Wiley Online Library
Classic concepts about the role of epicardial adipose tissue (EpAT) in heart physiology
include its role in cardiac metabolism, mechanical protection of coronaries, innervation and …

[HTML][HTML] Total adiponectin in overweight and obese subjects and its response to visceral fat loss

S Gariballa, J Alkaabi, J Yasin, A Al Essa - BMC endocrine disorders, 2019 - Springer
Background Visceral obesity and related diabetes is reaching epidemic proportions in the
United Arab Emirates (UAE). Adiponectin is a hormone that is secreted by adipose tissue …

[HTML][HTML] Obesity and diabetes are major risk factors for epicardial adipose tissue inflammation

V Vyas, H Blythe, EG Wood, B Sandhar, SJ Sarker… - JCI insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Epicardial adipose tissue (EAT) directly overlies the myocardium, with
changes in its morphology and volume associated with myriad cardiovascular and metabolic …

[HTML][HTML] Adiponectin system (rescue hormone): The missing link between metabolic and cardiovascular diseases

MA Aljafary, EA Al-Suhaimi - Pharmaceutics, 2022 - mdpi.com
The adipose tissue, regardless of its role in generating and storing energy, acts as a key
player as an endocrine tissue, producing a wide scale of cytokines/hormones called …

The interplay between adipose tissue and the cardiovascular system: is fat always bad?

I Akoumianakis, C Antoniades - Cardiovascular research, 2017 - academic.oup.com
Obesity is a risk factor for cardiovascular disease (CVD). However, clinical research has
revealed a paradoxically protective role for obesity in patients with chronic diseases …

Cardiovascular disease prediction by machine learning algorithms based on cytokines in Kazakhs of China

Y Jiang, X Zhang, R Ma, X Wang, J Liu… - Clinical …, 2021 - Taylor & Francis
Background Cardiovascular disease (CVD) is the leading cause of mortality worldwide.
Accurately identifying subjects at high-risk of CVD may improve CVD outcomes. We sought …