Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer
N Li, X Zhang, J Zhou, W Li, X Shu, Y Wu… - Advanced Drug Delivery …, 2022 - Elsevier
A growing body of multiscale biomechanical studies has been proposed to highlight the
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …
How the mechanical microenvironment of stem cell growth affects their differentiation: A review
X Zhang, S Zhang, T Wang - Stem cell research & therapy, 2022 - Springer
Stem cell differentiation is of great interest in medical research; however, specifically and
effectively regulating stem cell differentiation is still a challenge. In addition to chemical …
effectively regulating stem cell differentiation is still a challenge. In addition to chemical …
Bone regeneration and oxidative stress: an updated overview
AE Bădilă, DM Rădulescu, A Ilie, AG Niculescu… - Antioxidants, 2022 - mdpi.com
Bone tissue engineering is a complex domain that requires further investigation and benefits
from data obtained over past decades. The models are increasing in complexity as they …
from data obtained over past decades. The models are increasing in complexity as they …
[HTML][HTML] Integrating physicomechanical and biological strategies for BTE: biomaterials-induced osteogenic differentiation of MSCs
Large bone defects are a major global health concern. Bone tissue engineering (BTE) is the
most promising alternative to avoid the drawbacks of autograft and allograft bone …
most promising alternative to avoid the drawbacks of autograft and allograft bone …
In vitro functional models for human liver diseases and drug screening: beyond animal testing
Liver is one of the most important and complex organs in the human body, being
characterized by a sophisticated microarchitecture and responsible for key physiological …
characterized by a sophisticated microarchitecture and responsible for key physiological …
Synthesis of ZnO nanoparticles on carbon graphite and its application as a highly efficient electrochemical nano-sensor for the detection of amoxicillin: analytical …
J Zoubir, I Bakas, A Assabbane - Nanotechnology for Environmental …, 2021 - Springer
Amoxicillin is an antimicrobial of the penicillin class discovered in 1928. The objective of this
paper is to construct a simple platform for electrocatalytic detection of amoxicillin using a …
paper is to construct a simple platform for electrocatalytic detection of amoxicillin using a …
A biomimetic renal fibrosis progression model on-chip evaluates anti-fibrotic effects longitudinally in a dynamic fibrogenic niche
D Wu, J Wu, H Liu, S Shi, L Wang, Y Huang, X Yu… - Lab on a Chip, 2023 - pubs.rsc.org
Although renal fibrosis can advance chronic kidney disease and progressively lead to end-
stage renal failure, no effective anti-fibrotic drugs have been clinically approved. To aid drug …
stage renal failure, no effective anti-fibrotic drugs have been clinically approved. To aid drug …
Assessment of human embryonic stem cells differentiation into definitive endoderm lineage on the soft substrates
Pluripotent stem cells (PSCs) hold enormous potential for treating multiple diseases owing
to their ability to self‐renew and differentiate into any cell type. Albeit possessing such …
to their ability to self‐renew and differentiate into any cell type. Albeit possessing such …
[HTML][HTML] Biophysical cues involved in the stem cell niche for stemness maintenance
C Li, L Zheng, Y Fan - Medicine in Novel Technology and Devices, 2024 - Elsevier
The characteristics of stem cells are self-renewal ability and differentiation potential. These
properties are defined as stemness, offering them application in tissue repair and …
properties are defined as stemness, offering them application in tissue repair and …
Fluid Flow Mechanical Stimulation-Assisted Cartridge Device for the Osteogenic Differentiation of Human Mesenchymal Stem Cells
Human mesenchymal stem cells (hMSCs) have the potential to differentiate into different
types of mesodermal tissues. In vitro proliferation and differentiation of hMSCs are …
types of mesodermal tissues. In vitro proliferation and differentiation of hMSCs are …