Obstructive sleep apnoea heterogeneity and cardiovascular disease
Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …
Obstructive sleep apnea in cardiovascular disease: a review of the literature and proposed multidisciplinary clinical management strategy
JR Tietjens, D Claman, EJ Kezirian… - Journal of the …, 2019 - Am Heart Assoc
Cardiovascular disease (CVD) remains a highly prevalent cause of morbidity and mortality,
both in the United States and worldwide. In parallel with the development of new and …
both in the United States and worldwide. In parallel with the development of new and …
Obstructive sleep apnea, cognition and Alzheimer's disease: a systematic review integrating three decades of multidisciplinary research
OM Bubu, AG Andrade, OQ Umasabor-Bubu… - Sleep medicine …, 2020 - Elsevier
Increasing evidence links cognitive-decline and Alzheimer's disease (AD) to various sleep
disorders, including obstructive sleep apnea (OSA). With increasing age, there are …
disorders, including obstructive sleep apnea (OSA). With increasing age, there are …
Phenotypic approaches to obstructive sleep apnoea–new pathways for targeted therapy
DJ Eckert - Sleep medicine reviews, 2018 - Elsevier
People develop obstructive sleep apnoea (OSA) for different reasons. The ability to
understand these reasons, easily identify them in individual patients, and develop therapies …
understand these reasons, easily identify them in individual patients, and develop therapies …
Adult obstructive sleep apnoea
AS Jordan, DG McSharry, A Malhotra - The Lancet, 2014 - thelancet.com
Obstructive sleep apnoea is an increasingly common disorder of repeated upper airway
collapse during sleep, leading to oxygen desaturation and disrupted sleep. Features include …
collapse during sleep, leading to oxygen desaturation and disrupted sleep. Features include …
Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets
Rationale: The pathophysiologic causes of obstructive sleep apnea (OSA) likely vary among
patients but have not been well characterized. Objectives: To define carefully the proportion …
patients but have not been well characterized. Objectives: To define carefully the proportion …
Pathophysiology of sleep apnea
JA Dempsey, SC Veasey, BJ Morgan… - Physiological …, 2010 - journals.physiology.org
Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …
Sleep apnea and cardiovascular disease: An American heart association/American college of cardiology foundation scientific statement from the American heart …
VK Somers, DP White, R Amin, WT Abraham, F Costa… - Circulation, 2008 - Am Heart Assoc
Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …
considerations. First, the close association between obesity and OSA often obscures …
Obstructive sleep apnea severity affects amyloid burden in cognitively normal elderly. A longitudinal study
Rationale: Recent evidence suggests that obstructive sleep apnea (OSA) may be a risk
factor for developing mild cognitive impairment and Alzheimer's disease. However, how …
factor for developing mild cognitive impairment and Alzheimer's disease. However, how …
Pathophysiology of adult obstructive sleep apnea
DJ Eckert, A Malhotra - Proceedings of the American thoracic …, 2008 - atsjournals.org
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive narrowing
or collapse of the pharyngeal airway during sleep. The disorder is associated with major …
or collapse of the pharyngeal airway during sleep. The disorder is associated with major …