Cancer neoantigens are antigens that result from somatic mutations present in individual
cancers. Neoantigens are considered important targets for cancer immunotherapy because …

Herpes simplex virus type-1 (HSV-1) and-2 (HSV-2) are highly prevalent global pathogens
which commonly cause recurrent oral and genital ulcerations. Less common but more …

Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) have co-evolved with humans for
thousands of years and are present at a high prevalence in the population worldwide. HSV …

Neoantigens are critical targets of antitumor T-cell responses. The ATLAS bioassay was
developed to identify neoantigens empirically by expressing each unique patient-specific …

Background Herpes simplex virus 2 (HSV2) causes genital herpes in> 400 million persons
worldwide. Methods We conducted a randomized, double-blinded, placebo-controlled trial …

Background. Genital herpes simplex virus type 2 (HSV-2) infection causes recurrent lesions
and frequent viral shedding. GEN-003 is a candidate therapeutic vaccine containing HSV-2 …

The Alphaherpesvirinae subfamily includes HSV types 1 and 2 and the sequence-divergent
pathogen varicella zoster virus (VZV). T cells, controlled by TCR and HLA molecules that …

Herpesviruses establish latent infections, and most reactivate frequently, resulting in
symptoms and virus shedding in healthy individuals. In immunocompromised patients …

Until recently, malaria vaccine development efforts have focused almost exclusively on a
handful of well characterized Plasmodium falciparum antigens. Despite dedicated work by …

Herpes simplex encephalitis (HSE) is a severe neurological disease in children and adults
caused by herpes simplex virus. This review discusses recent findings on the role of Toll-like …