Epithelial–mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease
Epithelial–mesenchymal transition (EMT) plays key roles during lung development and
many lung diseases such as chronic obstructive pulmonary disease (COPD), lung cancer …
many lung diseases such as chronic obstructive pulmonary disease (COPD), lung cancer …
[HTML][HTML] Early identification of chronic lung allograft dysfunction: the need of biomarkers
A growing number of patients with end-stage lung disease have benefited from lung
transplantation (LT). Improvements in organ procurement, surgical techniques and intensive …
transplantation (LT). Improvements in organ procurement, surgical techniques and intensive …
Reduction of primary graft dysfunction using cytokine adsorption during organ preservation and after lung transplantation
H Ghaidan, M Stenlo, A Niroomand… - Nature …, 2022 - nature.com
Despite improvements, lung transplantation remains hampered by both a scarcity of donor
organs and by mortality following primary graft dysfunction (PGD). Since acute respiratory …
organs and by mortality following primary graft dysfunction (PGD). Since acute respiratory …
Bronchiolitis obliterans syndrome after lung or haematopoietic stem cell transplantation: current management and future directions
Bronchiolitis obliterans syndrome (BOS) may develop after either lung or haematopoietic
stem cell transplantation (HSCT), with similarities in histopathological features and clinical …
stem cell transplantation (HSCT), with similarities in histopathological features and clinical …
Effector immune cells in chronic lung allograft dysfunction: A systematic review
Chronic lung allograft dysfunction (CLAD) remains the major barrier to long‐term survival
after lung transplantation and improved insight into its underlying immunological …
after lung transplantation and improved insight into its underlying immunological …
[HTML][HTML] Pseudomonas aeruginosa and acute rejection independently increase the risk of donor-specific antibodies after lung transplantation
HS Kulkarni, K Tsui, S Sunder, A Ganninger… - American Journal of …, 2020 - Elsevier
Factors contributing to donor-specific HLA antibody (DSA) development after lung
transplantation have not been systematically evaluated. We hypothesized that the isolation …
transplantation have not been systematically evaluated. We hypothesized that the isolation …
[HTML][HTML] The role of innate immunity in the long-term outcome of lung transplantation
M Kawashima, SC Juvet - Annals of translational medicine, 2020 - ncbi.nlm.nih.gov
Long-term survival after lung transplantation remains suboptimal due to chronic lung
allograft dysfunction (CLAD), a progressive scarring process affecting the graft. Although anti …
allograft dysfunction (CLAD), a progressive scarring process affecting the graft. Although anti …
[HTML][HTML] Development of a multivariate prediction model for early-onset bronchiolitis obliterans syndrome and restrictive allograft syndrome in lung transplantation
A Koutsokera, PJ Royer, JP Antonietti, A Fritz… - Frontiers in …, 2017 - frontiersin.org
Background Chronic lung allograft dysfunction and its main phenotypes, bronchiolitis
obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), are major causes of …
obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), are major causes of …
Immunological diversity in phenotypes of chronic lung allograft dysfunction: a comprehensive immunohistochemical analysis
E Vandermeulen, E Lammertyn… - Transplant …, 2017 - Wiley Online Library
Chronic rejection after organ transplantation is defined as a humoral‐and cell‐mediated
immune response directed against the allograft. In lung transplantation, chronic rejection is …
immune response directed against the allograft. In lung transplantation, chronic rejection is …
[HTML][HTML] Elevated cell-free DNA in respiratory viral infection and associated lung allograft dysfunction
K Bazemore, N Permpalung, J Mathew… - American Journal of …, 2022 - Elsevier
Respiratory viral infection (RVI) in lung transplant recipients (LTRs) is a risk for chronic lung
allograft dysfunction (CLAD). We hypothesize that donor-derived cell-free DNA …
allograft dysfunction (CLAD). We hypothesize that donor-derived cell-free DNA …