Biodegradable synthetic polymers: Preparation, functionalization and biomedical application

H Tian, Z Tang, X Zhuang, X Chen, X Jing - Progress in Polymer Science, 2012 - Elsevier
Biodegradable polymers have been widely used and have greatly promoted the
development of biomedical fields because of their biocompatibility and biodegradability. The …

Gene therapy and DNA delivery systems

D Ibraheem, A Elaissari, H Fessi - International journal of pharmaceutics, 2014 - Elsevier
Gene therapy is a promising new technique for treating many serious incurable diseases,
such as cancer and genetic disorders. The main problem limiting the application of this …

Dendrimers in gene delivery

C Dufès, IF Uchegbu, AG Schätzlein - Advanced drug delivery reviews, 2005 - Elsevier
Dendrimers have unique molecular architectures and properties that make them attractive
materials for the development of nanomedicines. Key properties such as defined …

Progress in developing cationic vectors for non-viral systemic gene therapy against cancer

M Morille, C Passirani, A Vonarbourg, A Clavreul… - Biomaterials, 2008 - Elsevier
Initially, gene therapy was viewed as an approach for treating hereditary diseases, but its
potential role in the treatment of acquired diseases such as cancer is now widely …

Inorganic nanoparticles as carriers of nucleic acids into cells

V Sokolova, M Epple - Angewandte chemie international …, 2008 - Wiley Online Library
The transfer of nucleic acids (DNA or RNA) into living cells, that is, transfection, is a major
technique in current biochemistry and molecular biology. This process permits the selective …

Polymers for gene delivery across length scales

D Putnam - Nature materials, 2006 - nature.com
A number of human diseases stem from defective genes. One approach to treating such
diseases is to replace, or override, the defective genes with normal genes, an approach …

[PDF][PDF] Vectors and delivery systems in gene therapy

R Gardlik, R Pálffy, J Hodosy, J Lukács, J Turna… - Med Sci …, 2005 - academia.edu
Gene therapy provides modern medicine with new perspectives that were unthinkable two
decades ago. Progress in molecular biology and, especially, molecular medicine is now …

Gene delivery with synthetic (non viral) carriers

MD Brown, AG Schätzlein, IF Uchegbu - International Journal of …, 2001 - Elsevier
Non-viral gene delivery involving the use of cationic polymer and cationic lipid based
carriers still continues to enjoy a high profile due to the safety advantages offered by these …

Plasmid copy number and plasmid stability

K Friehs - New trends and developments in biochemical …, 2004 - Springer
Many expression systems in research and industry use plasmids as vectors for the
production of recombinant proteins or non-proteinous recombinant substances. Plasmids …

Poly(l-lysine)-Modified Iron Oxide Nanoparticles for Stem Cell Labeling

M Babic, D Horák, M Trchová, P Jendelová… - Bioconjugate …, 2008 - ACS Publications
New surface-modified iron oxide nanoparticles were developed by precipitation of Fe (II)
and Fe (III) salts with ammonium hydroxide and oxidation of the resulting magnetite with …