[HTML][HTML] Impact of heavy metals on the environment and human health: Novel therapeutic insights to counter the toxicity

S Mitra, AJ Chakraborty, AM Tareq, TB Emran… - Journal of King Saud …, 2022 - Elsevier
Heavy metals are well-known environmental pollutants owing to their toxicity, longevity in
the atmosphere, and ability to accumulate in the human body via bioaccumulation. The …

Metal toxicity links to Alzheimer's disease and neuroinflammation

TJ Huat, J Camats-Perna, EA Newcombe… - Journal of molecular …, 2019 - Elsevier
As the median age of the population increases, the number of individuals with Alzheimer's
disease (AD) and the associated socio-economic burden are predicted to worsen. While …

Cadmium toxicity and health effects—a brief summary

AE Charkiewicz, WJ Omeljaniuk, K Nowak, M Garley… - Molecules, 2023 - mdpi.com
Cadmium (Cd) is a ductile metal in the form of a blueish or silvery-white powder. It is
naturally found in soil (about 0.2 mg/kg), minerals, and water. Cd belongs to the group of …

Heavy metals exposure and Alzheimer's disease and related dementias

KM Bakulski, YA Seo, RC Hickman… - Journal of …, 2020 - content.iospress.com
Alzheimer's disease and related dementias lack effective treatment or cures and are major
public health challenges. Risk for Alzheimer's disease and related dementias is partially …

Heavy metal mixture exposure and effects in developing nations: an update

BO Anyanwu, AN Ezejiofor, ZN Igweze, OE Orisakwe - Toxics, 2018 - mdpi.com
The drive for development and modernization has come at great cost. Various human
activities in developed and developing countries, particularly in sub-Saharan Africa (SSA) …

Heavy metals (Pb, Cd, As and MeHg) as risk factors for cognitive dysfunction: A general review of metal mixture mechanism in brain

V Karri, M Schuhmacher, V Kumar - Environmental toxicology and …, 2016 - Elsevier
Human exposure to toxic heavy metals is a global challenge. Concurrent exposure of heavy
metals, such as lead (Pb), cadmium (Cd), arsenic (As) and methylmercury (MeHg) are …

Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases

M Chin-Chan, J Navarro-Yepes… - Frontiers in cellular …, 2015 - frontiersin.org
Neurodegenerative diseases including Alzheimer (AD) and Parkinson (PD) have attracted
attention in last decades due to their high incidence worldwide. The etiology of these …

Cadmium-induced oxidative stress: focus on the central nervous system

JJV Branca, C Fiorillo, D Carrino, F Paternostro… - Antioxidants, 2020 - mdpi.com
Cadmium (Cd), a category I human carcinogen, is a well-known widespread environmental
pollutant. Chronic Cd exposure affects different organs and tissues, such as the central …

Role of heavy metals (copper (Cu), arsenic (As), cadmium (Cd), iron (Fe) and lithium (Li)) induced neurotoxicity

B Vellingiri, A Suriyanarayanan, P Selvaraj… - Chemosphere, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative condition characterized by the dopamine
(DA) neuronal loss in the substantia nigra. PD impairs motor controls symptoms such as …

Cadmium-induced neurotoxicity: still much ado

JJV Branca, G Morucci, A Pacini - Neural regeneration research, 2018 - journals.lww.com
Cadmium (Cd) is a highly toxic heavy metal that accumulates in living system and as such is
currently one of the most important occupational and environmental pollutants. Cd reaches …