The sponge holobiont in a changing ocean: from microbes to ecosystems

L Pita, L Rix, BM Slaby, A Franke, U Hentschel - Microbiome, 2018 - Springer
The recognition that all macroorganisms live in symbiotic association with microbial
communities has opened up a new field in biology. Animals, plants, and algae are now …

Actinomycetes: still a source of novel antibiotics

O Genilloud - Natural product reports, 2017 - pubs.rsc.org
Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …

Small molecules from the human microbiota

MS Donia, MA Fischbach - Science, 2015 - science.org
BACKGROUND Two developments in distinct fields are converging to create interest in
discovering small molecules from the human microbiome. First, the use of genomics to guide …

Antibiotics and bacterial resistance in the 21st century

RJ Fair, Y Tor - Perspectives in medicinal chemistry, 2014 - journals.sagepub.com
Dangerous, antibiotic resistant bacteria have been observed with increasing frequency over
the past several decades. In this review the factors that have been linked to this …

Natural products: a continuing source of novel drug leads

GM Cragg, DJ Newman - Biochimica et Biophysica Acta (BBA)-General …, 2013 - Elsevier
BACKGROUND: Nature has been a source of medicinal products for millennia, with many
useful drugs developed from plant sources. Following discovery of the penicillins, drug …

[图书][B] Biology and evolution of the mollusca, volume 1

WF Ponder, DR Lindberg, JM Ponder - 2019 - taylorfrancis.com
Molluscs comprise the second largest phylum of animals (after arthropods), occurring in
virtually all habitats. Some are commercially important, a few are pests and some carry …

Marketed marine natural products in the pharmaceutical and cosmeceutical industries: Tips for success

A Martins, H Vieira, H Gaspar, S Santos - Marine drugs, 2014 - mdpi.com
The marine environment harbors a number of macro and micro organisms that have
developed unique metabolic abilities to ensure their survival in diverse and hostile habitats …

Marine bacterial secondary metabolites: A treasure house for structurally unique and effective antimicrobial compounds

R Srinivasan, A Kannappan, C Shi, X Lin - Marine Drugs, 2021 - mdpi.com
The prevalence of antimicrobial resistance reduces the effectiveness of antimicrobial drugs
in preventing and treating infectious diseases caused by pathogenic organisms, such as …

Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactives

MF Mehbub, J Lei, C Franco, W Zhang - Marine drugs, 2014 - mdpi.com
Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest
animals are the single best source of marine natural products. The present review presents …

[HTML][HTML] Metabolic potential of endophytic bacteria

G Brader, S Compant, B Mitter, F Trognitz… - Current opinion in …, 2014 - Elsevier
Highlights•Endophytes are a source of a plethora of biologically active substances.•
Endophyte-associated metabolites may be needed for the interaction with the plant.•Some …