[PDF][PDF] Elucidating mechanisms of drug-resistant Plasmodium falciparum
LS Ross, DA Fidock - Cell host & microbe, 2019 - cell.com
Intensified treatment and control efforts since the early 2000s have dramatically reduced the
burden of Plasmodium falciparum malaria. However, drug resistance threatens to derail this …
burden of Plasmodium falciparum malaria. However, drug resistance threatens to derail this …
The genomic architecture of antimalarial drug resistance
AN Cowell, EA Winzeler - Briefings in functional genomics, 2019 - academic.oup.com
Plasmodium falciparum and Plasmodium vivax, the two protozoan parasite species that
cause the majority of cases of human malaria, have developed resistance to nearly all …
cause the majority of cases of human malaria, have developed resistance to nearly all …
Essential genes of the parasitic apicomplexa
Genome-scale mutagenesis screens for genes essential for apicomplexan parasite survival
have been completed in three species: Plasmodium falciparum, the major human malaria …
have been completed in three species: Plasmodium falciparum, the major human malaria …
Selection of Plasmodium falciparum cytochrome B mutants by putative PfNDH2 inhibitors
Malaria control is threatened by a limited pipeline of effective pharmaceuticals against drug-
resistant strains of Plasmodium falciparum. Components of the mitochondrial electron …
resistant strains of Plasmodium falciparum. Components of the mitochondrial electron …
[HTML][HTML] Using an antimalarial in mosquitoes overcomes Anopheles and Plasmodium resistance to malaria control strategies
DG Paton, AS Probst, E Ma, KL Adams… - PLoS …, 2022 - journals.plos.org
The spread of insecticide resistance in Anopheles mosquitoes and drug resistance in
Plasmodium parasites is contributing to a global resurgence of malaria, making the …
Plasmodium parasites is contributing to a global resurgence of malaria, making the …
[HTML][HTML] Using the Plasmodium mitochondrial genome for classifying mixed-species infections and inferring the geographical origin of P. falciparum parasites …
SE Schmedes, D Patel, J Kelley, V Udhayakumar… - PloS one, 2019 - journals.plos.org
The ability to identify mixed-species infections and track the origin of Plasmodium parasites
can further enhance the development of treatment and prevention recommendations as well …
can further enhance the development of treatment and prevention recommendations as well …
Plasmodium Ape1 is a multifunctional enzyme in mitochondrial base excision repair and is required for efficient transition from liver to blood stage infection
The malaria parasite has a single mitochondrion which carries multiple tandem repeats of its
6 kb genome encoding three proteins of the electron transport chain. There is little …
6 kb genome encoding three proteins of the electron transport chain. There is little …
Selection of Cytochrome b Mutants Is Rare among Plasmodium falciparum Patients Failing Treatment with Atovaquone-Proguanil in Cambodia
JT Lin, A Waltmann, KA Moser, Z Park… - Antimicrobial agents …, 2021 - Am Soc Microbiol
Atovaquone-proguanil remains effective against multidrug-resistant Plasmodium falciparum
in Southeast Asia, but resistance is mediated by a single point mutation in cytochrome b …
in Southeast Asia, but resistance is mediated by a single point mutation in cytochrome b …
[HTML][HTML] Template copy number and the sensitivity of quantitative PCR for Plasmodium falciparum in asymptomatic individuals
TA Thompson, MB Touré, D Sanogo, JG Shaffer… - Malaria Journal, 2020 - Springer
Background The identification of asymptomatic individuals with Plasmodium falciparum
infection is difficult because they do not seek medical treatment and often have too few …
infection is difficult because they do not seek medical treatment and often have too few …
Antimalarials in mosquitoes overcome Anopheles and Plasmodium resistance to malaria control strategies
The spread of insecticide resistance in Anopheles mosquitoes and drug resistance in
Plasmodium parasites is contributing to a global resurgence of malaria, making the …
Plasmodium parasites is contributing to a global resurgence of malaria, making the …