The cardiovascular effects of erythropoietin

KJ Smith, AJ Bleyer, WC Little… - Cardiovascular …, 2003 - academic.oup.com
Erythropoietin is a hypoxia-induced hormone that is essential for normal erythropoiesis. The
production of recombinant human erythropoietin (rHuEpo) has revolutionized the treatment …

Alternative erythropoietin receptors in the nervous system

D Ostrowski, R Heinrich - Journal of clinical medicine, 2018 - mdpi.com
In addition to its regulatory function in the formation of red blood cells (erythropoiesis) in
vertebrates, Erythropoietin (Epo) contributes to beneficial functions in a variety of non …

Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality

N Suzuki, O Ohneda, S Takahashi… - Blood, The Journal …, 2002 - ashpublications.org
Erythropoietin (Epo) and its receptor (EpoR) are indispensable to erythropoiesis. Although
roles besides angiogenesis, such as neuroprotection and heart development, have been …

Expression of erythropoietin receptor splice variants in human cancer

MO Arcasoy, X Jiang, ZA Haroon - Biochemical and biophysical research …, 2003 - Elsevier
Erythropoietin (EPO) regulates mammalian erythropoiesis by binding to its transmembrane
receptor EPOR. Recent studies demonstrated functional EPOR expression in human cancer …

Anemia as the main manifestation of myelodysplastic syndromes

V Santini - Seminars in hematology, 2015 - Elsevier
Myelodysplastic syndromes (MDS) are a constellation of different diseases sharing anemia
in the great majority of cases, and this cytopenia defines these pathologies and their most …

Low doses of EPO activate MAP kinases but not JAK2–STAT5 in rat vascular smooth muscle cells

F Ammarguellat, M Llovera, PA Kelly, V Goffin - … and biophysical research …, 2001 - Elsevier
Previous reports have shown a direct effect of erythropoietin (Epo) on vascular smooth
muscle cells (VSMCs). Our aim was to assess expression of the Epo receptor (EpoR) on …

Erythropoietin and co.: intrinsic structure and functional disorder

VN Uversky, EM Redwan - Molecular BioSystems, 2017 - pubs.rsc.org
Erythropoietin (Epo) is a heavily glycosylated protein, with its main function being related to
erythropoiesis, where it controls red blood cell production via interaction with the Epo …

Proteomic analysis reveals autophagy as pro-survival pathway elicited by long-term exposure with 5-azacitidine in high-risk myelodysplasia

A Romano, C Giallongo, P La Cava… - Frontiers in …, 2017 - frontiersin.org
Azacytidine (5-AZA) is the standard first-choice treatment for high-risk myelodysplasia (MDS)
patients. However, the clinical outcome for those patients who interrupt treatment or whose …

[HTML][HTML] Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells

N Pregi, D Vittori, G Pérez, CP Leirós… - Biochimica et Biophysica …, 2006 - Elsevier
Since apoptosis appeared to be related to neurodegenerative processes, neuroprotection
has been involved in investigation of therapeutic approaches focused upon …

Prevention of erythropoietin-associated hypertension

MS Lee, JS Lee, JY Lee - Hypertension, 2007 - Am Heart Assoc
Hypertension is the most significant complication from treatment with erythropoietin (Epo).
Can Epo-induced hypertension be eliminated? We examined systemic and local effects of …