Translational research in traumatic brain injury
D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …
contributing to nearly one-third of all injury related deaths in the United States and exacting …
Epilepsy in poor regions of the world
CR Newton, HH Garcia - The Lancet, 2012 - thelancet.com
Epilepsy is a common disorder, particularly in poor areas of the world, and can have a
devastating effect on people with the disorder and their families. The burden of epilepsy in …
devastating effect on people with the disorder and their families. The burden of epilepsy in …
UNC13B variants associated with partial epilepsy with favourable outcome
J Wang, JD Qiao, XR Liu, DT Liu, YH Chen, Y Wu… - Brain, 2021 - academic.oup.com
The unc-13 homolog B (UNC13B) gene encodes a presynaptic protein, mammalian
uncoordinated 13-2 (Munc13-2), which is highly expressed in the brain—predominantly in …
uncoordinated 13-2 (Munc13-2), which is highly expressed in the brain—predominantly in …
Neuroinflammation in post-traumatic epilepsy: pathophysiology and tractable therapeutic targets
Epilepsy is a common chronic consequence of traumatic brain injury (TBI), contributing to
increased morbidity and mortality for survivors. As post-traumatic epilepsy (PTE) is drug …
increased morbidity and mortality for survivors. As post-traumatic epilepsy (PTE) is drug …
Astrocytes exhibit a protective role in neuronal firing patterns under chemically induced seizures in neuron–astrocyte co-cultures
A Ahtiainen, B Genocchi, JMA Tanskanen… - International journal of …, 2021 - mdpi.com
Astrocytes and neurons respond to each other by releasing transmitters, such as γ-
aminobutyric acid (GABA) and glutamate, that modulate the synaptic transmission and …
aminobutyric acid (GABA) and glutamate, that modulate the synaptic transmission and …
[HTML][HTML] Neurological disorders
Neurological disorders pose a large burden on worldwide health. The most recent estimates
show that the neurological disorders included in the Global Burden of Disease (GBD) Study …
show that the neurological disorders included in the Global Burden of Disease (GBD) Study …
Toward the use of novel alternative methods in epilepsy modeling and drug discovery
C Miguel Sanz, M Martinez Navarro… - Frontiers in …, 2023 - frontiersin.org
Epilepsy is a chronic brain disease and, considering the amount of people affected of all
ages worldwide, one of the most common neurological disorders. Over 20 novel antiseizure …
ages worldwide, one of the most common neurological disorders. Over 20 novel antiseizure …
Neonatal hyperbilirubinemia and the risk of febrile seizures and childhood epilepsy
RD Maimburg, J Olsen, Y Sun - Epilepsy research, 2016 - Elsevier
Purpose The aim of the study was to estimate the association between newborn children
treated with phototerapy for hyperbilirubinemia and the subsequent risk of febrile seizures or …
treated with phototerapy for hyperbilirubinemia and the subsequent risk of febrile seizures or …
Postencephalitic epilepsy: clinical characteristics and predictors
TD Singh, JE Fugate, SE Hocker, AA Rabinstein - Epilepsia, 2015 - Wiley Online Library
Objective To describe the etiologies, clinical presentations, outcomes, and predictors of
postencephalitic epilepsy (PE) in a large series of adult patients with acute encephalitis …
postencephalitic epilepsy (PE) in a large series of adult patients with acute encephalitis …
Neuro-immune crosstalk in drug-resistant epilepsy
BM Andersen, FJ Quintana - Nature Neuroscience, 2022 - nature.com
Epilepsy is the most common childhood neurological disease, and nearly 20% of affected
children develop drug-resistant childhood epilepsy (DRCE). Using single-cell analysis …
children develop drug-resistant childhood epilepsy (DRCE). Using single-cell analysis …