[HTML][HTML] The roles of hepatokine and osteokine in liver-bone crosstalk: Advance in basic and clinical aspects

Z Li, X Wen, N Li, C Zhong, L Chen, F Zhang… - Frontiers in …, 2023 - frontiersin.org
Both the liver and bone are important secretory organs in the endocrine system. By secreting
organ factors (hepatokines), the liver regulates the activity of other organs. Similarly, bone …

[HTML][HTML] Molecular Regulation of Thermogenic Mechanisms in Beige Adipocytes

S Yang, Y Liu, X Wu, R Zhu, Y Sun, S Zou… - International Journal of …, 2024 - mdpi.com
Adipose tissue is conventionally recognized as a metabolic organ responsible for storing
energy. However, a proportion of adipose tissue also functions as a thermogenic organ …

[HTML][HTML] Therapeutic target analysis and molecular mechanism of melatonin-treated leptin resistance induced obesity: A Systematic Study of Network Pharmacology

V Suriagandhi, V Nachiappan - Frontiers in Endocrinology, 2022 - frontiersin.org
Background Obesity is a medical problem with an increased risk for other metabolic
disorders like diabetes, heart problem, arthritis, etc. Leptin is an adipose tissue-derived …

肝脏分泌因子与代谢性疾病

梁佳琦, 刘畅, 张雯翔, 陈思禹 - 遗传, 2022 - chinagene.cn
代谢性疾病泛指代谢功能发生问题所引起的疾病, 其主要症状包括中心性肥胖, 胰岛素抵抗,
血脂血糖异常, 血压升高等. 肝脏作为人体内一个重要的代谢器官, 在调节全身葡萄糖和脂质代谢 …

Cold stress causes liver damage by inducing ferroptosis through the p38 MAPK/Drp1 pathway

Y Huang, K Xiong, A Wang, Z Wang, Q Cui, H Xie… - Cryobiology, 2023 - Elsevier
Acute extreme cold exposure impairs human health and even causes hypothermia which
threatens human life. Liver, as a hub in metabolism and thermogenesis, is vital for cold …

[HTML][HTML] Navigating the Adipocyte Precursor Niche: Cell-Cell Interactions, Regulatory Mechanisms and Implications for Adipose Tissue Homeostasis

D Kesharwani, AC Brown - Journal of cellular signaling, 2024 - ncbi.nlm.nih.gov
Support for stem cell self-renewal and differentiation hinges upon the intricate
microenvironment termed the stem cell 'niche'. Within the adipose tissue stem cell niche …

白色脂肪棕色化对非酒精性脂肪性肝病的影响.

赵晨露, 周铖, 尚东方, 刘素彤… - Journal of Clinical …, 2023 - search.ebscohost.com
非酒精性脂肪性肝病(NAFLD) 是由于脂肪代谢功能异常而出现大量脂肪类物质在肝细胞中蓄积
的慢性肝病. 常规的抗炎降酶治疗效果不佳, 恢复人体脂类物质的正常生物合成与代谢是NAFLD …

[HTML][HTML] 白色脂肪棕色化的研究进展

沈天娇, 杨刚毅 - Advances in Clinical Medicine, 2024 - hanspub.org
白色脂肪组织和棕色脂肪组织是哺乳动物体内两种主要的脂肪类型, 它们在结构,
分布和功能上存在显著差异, 对体内能量平衡的调控有着重要的影响. 米色脂肪细胞作为介于这 …

[HTML][HTML] The pan-liver network theory: From traditional chinese medicine to western medicine

Y Zhang, XM Fang - Journal of Physiological Investigation, 2023 - journals.lww.com
In traditional Chinese medicine (TCM), the liver is the “general organ” that is responsible for
governing/maintaining the free flow of qi over the entire body and storing blood. According to …

Influence of white fat browning on nonalcoholic fatty liver disease

Z Cheng, D SHANG, LIU Sutong, SHI Junhao - 临床肝胆病杂志, 2023 - lcgdbzz.org
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease in which a large amount
of fat accumulates in hepatocytes due to lipid metabolism disorders. Conventional anti …