Factor XIII (FXIII) is unique among clotting factors for a number of reasons: 1) it is a
protransglutaminase, which becomes activated in the last stage of coagulation; 2) it works …

Factor XIII (FXIII) is a transglutaminase enzyme that catalyses the formation of ε-(γ-glutamyl)
lysyl isopeptide bonds into protein substrates. The plasma form, FXIIIA2B2, has an …

The clinical importance of fibrin stabilizing factor ago, when Barkan and Gaspar [1]
demonbecame apparent when in 1960 Duckert and colstrated that fibrin clots that were …

As the third most common vascular disease, venous thromboembolism is associated with
significant mortality and morbidity. Pathogenesis underlying venous thrombosis is still not …

Expression of tissue transglutaminase (transglutaminase II, tTG) was shown to increase
drastically during monocyte differentiation into macrophages; however, its role in monocytic …

The immunocytochemical identification and characterization of indigenous dermal dendritic
cells (dermal dendrocytes) using a rabbit polyclonal antibody to clotting enzyme factor XIII …

Review Page 1 Review FACTOR XIII DEFICIENCY Factor XIII (FXIII) is the last enzyme in the
clotting cascade. Its main function is to convert the loose fibrin polymer into a firm, highly …

Factor XIII (XIII), an enzyme found in plasma (present as a pro-enzyme), platelets and
monocytes, is essential for normal haemostasis. It may also have a role to play in the …

Blood coagulation factor XIII (FXIII) is a protransglutaminase that becomes activated by the
concerted action of thrombin and Ca2+ in the final stage of the clotting cascade. In addition …

Congenital deficiency in coagulation factor XIII is a rare autosomal recessive bleeding
disorder. Although the defect was characterized over 30 years ago, little is known about the …