Memories allow experiences to have some permanence in our minds. Increasing adult
neurogenesis in the dentate gyrus of the hippocampus has been shown to reduce this …

Efforts to understand the role of the dentate gyrus have been hampered by the limitation of
extracellular recordings to identify cell types. By combining extracellular recording with …

The hippocampus is known to be involved in memory formation, storage and consolidation
22 (Squire et al., 2004), but its specific functionalities remain a mystery. One such …

The hippocampus plays a key role in pattern separation, the process of transforming similar
incoming information to highly dissimilar, non-overlapping representations. Sparse firing …

Background Aging is typically accompanied by memory decline and changes in
hippocampal function. Among these changes is a decline in the activity of the dentate gyrus …

Computational models combined with electrophysiological studies have informed our
understanding about the role of hippocampal subfields (dentate gyrus, DG; CA subfields …

Recent studies have reported that competitive endogenous RNAs (ceRNAs) can act as
sponges for a microRNA (miRNA) through their binding sites and that changes in ceRNA …

The hippocampus is a curved structure located in the medial temporal lobe of the brain.
Since the historic case of HM the hippocampus has been implicated in the processing of …

The Morris water maze (MWM) is a widely known, simple and effective task in the
examination of spatial learning and memory. Successful acquisition of the task is thought to …