Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

Current therapies for heart failure after myocardial infarction are limited and non-curative.
Although regenerative approaches are receiving significant attention, clinical efforts that …

Background—The lymphatic system regulates interstitial tissue fluid balance, and lymphatic
malfunction causes edema. The heart has an extensive lymphatic network displaying a …

The lymphatic vasculature, which accompanies the blood vasculature in most organs, is
indispensable in the maintenance of tissue fluid homeostasis, immune cell trafficking, and …

Ischemic cardiomyopathy (ICM) is the leading cause of heart failure worldwide, yet the
cellular and molecular signature of this disease is largely unclear. Using single-nucleus …

Objective: Lymphatics play an essential pathophysiological role in promoting fluid and
immune cell tissue clearance. Conversely, immune cells may influence lymphatic function …

In recent years, there has been increasing interest in the role of lymphatics in organ repair
and regeneration, due to their importance in immune surveillance and fluid homeostasis …

Lymphatic vessels, comprising the secondary circulatory system in human body, play a
multifaceted role in maintaining homeostasis among various tissues and organs. They are …

The mammalian heart contains multiple cell types that appear progressively during
embryonic development. Advance in determining cardiac lineage diversification has often …

In recent decades, treatments for myocardial infarction (MI), such as stem and progenitor cell
therapy, have attracted considerable scientific and clinical attention but failed to improve …