Ipa1 is an RNA polymerase II elongation factor that facilitates termination by maintaining levels of the poly (A) site endonuclease Ysh1
EL Pearson, JH Graber, SD Lee, KS Naggert… - Cell reports, 2019 - cell.com
The yeast protein Ipa1 was recently discovered to interact with the Ysh1 endonuclease of
the pre-mRNA cleavage and polyadenylation (C/P) machinery, and Ipa1 mutation impairs …
the pre-mRNA cleavage and polyadenylation (C/P) machinery, and Ipa1 mutation impairs …
Distinct roles of Pcf11 zinc-binding domains in pre-mRNA 3′-end processing
J Guéguéniat, AF Dupin, J Stojko… - Nucleic Acids …, 2017 - academic.oup.com
New transcripts generated by RNA polymerase II (RNAPII) are generally processed in order
to form mature mRNAs. Two key processing steps include a precise cleavage within the 3 …
to form mature mRNAs. Two key processing steps include a precise cleavage within the 3 …
The regulatory role of Pcf11-similar-4 (PCFS4) in Arabidopsis development by genome-wide physical interactions with target loci
Background The yeast and human Pcf11 functions in both constitutive and regulated
transcription and pre-mRNA processing. The constitutive roles of PCF11 are largely …
transcription and pre-mRNA processing. The constitutive roles of PCF11 are largely …
Multiple Transcripts from a 3′-UTR Reporter Vary in Sensitivity to Nonsense-Mediated mRNA Decay in Saccharomyces cerevisiae
JM Zaborske, B Zeitler, MR Culbertson - PLoS One, 2013 - journals.plos.org
Nonsense-mediated mRNA decay (NMD) causes accelerated transcript degradation when a
premature translation termination codon disrupts the open reading frame (ORF). Although …
premature translation termination codon disrupts the open reading frame (ORF). Although …
The functional complexity of the RNA-binding protein Yra1: mRNA biogenesis, genome stability and DSB repair
V Infantino, F Stutz - Current genetics, 2020 - Springer
The mRNA export adaptor Yra1 is essential in S. cerevisiae, and conserved from yeast to
human (ALY/REF). It is well characterized for its function during transcription elongation, 3 …
human (ALY/REF). It is well characterized for its function during transcription elongation, 3 …
[PDF][PDF] Effects of Tho2, a component of THO complex, on growth and mRNA export in fission yeast
EJ Koh, JH Yoon - Korean Journal of Microbiology, 2015 - koreascience.kr
Tho2/THOC2 is a subunit of the THO complex that plays important roles in mRNP
biogenesis connecting transcription with mRNA maturation and export. A fission yeast …
biogenesis connecting transcription with mRNA maturation and export. A fission yeast …
The deubiquitylase Ubp15 couples transcription to mRNA export
F Eyboulet, C Jeronimo, J Côté, F Robert - Elife, 2020 - elifesciences.org
Nuclear export of messenger RNAs (mRNAs) is intimately coupled to their synthesis. pre-
mRNAs assemble into dynamic ribonucleoparticles as they are being transcribed …
mRNAs assemble into dynamic ribonucleoparticles as they are being transcribed …
Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components
The process of tRNA splicing entails removal of an intron by TSEN (tRNA–splicing
endonuclease) and ligation of the resulting exon halves to generate functional tRNAs. In …
endonuclease) and ligation of the resulting exon halves to generate functional tRNAs. In …
Eukaryotic gene expression by RNA polymerase II
G Durairaj, S Malik, SR Bhaumik* - … Regulation, Epigenetics and …, 2017 - Wiley Online Library
This chapter provides an overview of the steps of eukaryotic gene expression by RNA
polymerase II, from the birth to the end of mRNA life. Transcriptional initiation of RNA …
polymerase II, from the birth to the end of mRNA life. Transcriptional initiation of RNA …