Growing evidence highlights the relevance of microbiota-gut-brain axis in the maintenance
of brain homeostasis as well as in the pathophysiology of major neurological and psychiatric …

Type 2 diabetes (T2D) is one of the main current threats to human health. Both T2D and its
numerous clinical complications are related to mitochondrial dysfunction and oxidative …

Background. This study is aimed at investigating the changes in relevant pathways and the
differential expression of related gene expression after ischemic stroke (IS) at the single‐cell …

In the panorama of inflammatory arthritis, gout is the most common and studied disease. It is
known that hyperuricemia and monosodium urate (MSU) crystal-induced inflammation …

The nucleotide-binding domain leucine-rich repeat and pyrin domain containing receptor
protein 3 (NLRP3) is an important pattern recognition receptor in human innate immunity …

The exact mechanism of myocardial hypertrophy has not been completely elucidated. NOD-
like receptor protein 3 (NLRP3) and the pyroptotic cascade play a critical role in cardiac …

Growing evidence suggests the involvement of the microbiota-gut-brain axis in cognitive
impairment induced by sleep deprivation (SD), however how the microbiota-gut-brain axis …

Evidence suggests that various innate immune system components are involved in
pathological inflammatory conditions. Among these components, the NLR family pyrin …

Diabetes mellitus (DM) ranks seventh as a cause of death worldwide. Chronic
complications, including cardiovascular, renal, and eye disease, as well as DM-associated …

Chronic inflammation might correlate with the formation of α-synuclein oligomers,
subsequently leading to dopaminergic (DA) neuronal death in Parkinson's disease (PD). As …