Among the most widely used models of Parkinson's disease (PD) are those that employ
toxins, especially 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP). Depending on the …

In recent years our understanding of Parkinson's disease has expanded both in terms of
pathological hallmarks as well as relevant genetic influences. In parallel with the aetiological …

Abstract Ginsenoside Rg1 (Rg1) is a major bioactive ingredient in Panax ginseng that has
low toxicity and has been shown to have neuroprotective effects. The objectives of the …

Epigallocatechin-3-gallate (EGCG) is the most widely studied catechin in green tea and has
been identified to regulate immune function. The objective of the present study was to …

Despite the different animal models of Parkinson's disease developed during the last years,
they still present limitations modelling the slow and progressive process of …

Rapamycin protects mice against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-
induced loss of dopaminergic neurons, which is an established model for Parkinson's …

The fight against neurodegenerative diseases, including Parkinson's disease (PD), is
among the global challenges of the 21st century. The low efficiency of therapy is due to the …

Motor dysfunction is a hallmark of Parkinson's disease (PD); however, non-motor symptoms
such as gastrointestinal dysfunction often arise prior to motor symptoms. Alterations in the …

Background We have shown previously that near-infrared light (NIr) treatment or
photobiomodulation neuroprotects dopaminergic cells in substantia nigra pars compacta …

Parkinson's disease (PD) is a movement disorder whose cardinal motor symptoms arise due
to the progressive loss of dopamine. Although this dopamine loss typically progresses …