Sepsis, a critical condition marked by systemic inflammation, profoundly impacts both innate
and adaptive immunity, often resulting in lymphopenia. This immune alteration can spare …

Acute infections cause local and systemic disorders which can lead in the most severe forms
to multi-organ failure and eventually to death. The host response to infection encompasses a …

Sepsis is a systemic inflammatory response syndrome, and severe cases often present with
inadequate organ perfusion and multiple organ failure. The interplay of inflammation and …

Conventionally, immune responses are studied in the context of inflamed tissues and their
corresponding draining lymph nodes (LNs). However, little is known about the effects of …

Macrophages play a pivotal role in immune responses, particularly in the context of
combating microbial threats within tissues. The identification of reliable biomarkers …

abstract Acute infections cause local and systemic disorders which can lead in the most
severe forms to multi-organ failure and eventually to death. The host response to infection …