MiTF/TFE translocation renal cell carcinoma (tRCC) is a rare and aggressive subtype of
RCC representing the most prevalent RCC in the pediatric population (up to 40%) and …

The process of tumorigenesis can be described by a series of molecular features, among
which alteration of cellular metabolism has recently emerged. This metabolic rewiring fulfills …

Renal cell carcinoma (RCC) is infrequent in the pediatric population. In addition, till date,
only a few reports have summarized the characteristics of pediatric RCC and differences …

Background A growing body of evidence suggests that age and gender play a role in cancer
outcomes. The objective of this study was to investigate the effect of age and gender on …

Discussion Renal cell carcinoma is a common urological malignancy with a high frequency
of invasion and metastasis at the time of diagnosis; however, it is relatively rare in children …

Purpose TFE3-rearranged/TFEB-altered renal cell carcinoma (RCC) is a rare subtype of
RCC. Due to its rarity, there is an unmet medical need for effective therapies in advanced …

Xp11. 2 translocation renal cell carcinoma (RCC) with transcription factor E3 (TFE3) gene
fusion is a rare tumor, and the prognosis of this tumor is poorer compared with that of other …

Renal neoplasms largely favor male patients; however, there is a growing list of tumors that
are more frequently diagnosed in females. These tumors include metanephric adenoma …

Objective Translocation renal cell carcinoma (TRCC) represents 1% to 5% of all cases of
renal cell carcinoma (RCC), with the highest frequency among children and young adults …

Clinical Practice Points• The 6p21 TFEB tRCC is an extremely rare carcinoma. The first case
of 6p21 TFEB tRCC was published in 2014. Since then, only no more than 80 additional …