The rising problem of antimicrobial resistance in the intensive care unit
N Brusselaers, D Vogelaers, S Blot - Annals of intensive care, 2011 - Springer
Mainly due to its extremely vulnerable population of critically ill patients, and the high use of
(invasive) procedures, the intensive care unit (ICU) is the epicenter of infections. These …
(invasive) procedures, the intensive care unit (ICU) is the epicenter of infections. These …
Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies
Patients in intensive care units (ICUs) are at high risk for healthcare-acquired infections
(HAI) due to the high prevalence of invasive procedures and devices, induced …
(HAI) due to the high prevalence of invasive procedures and devices, induced …
De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock
J Garnacho-Montero, A Gutiérrez-Pizarraya… - Intensive care …, 2014 - Springer
Purposes We set out to assess the safety and the impact on in-hospital and 90-day mortality
of antibiotic de-escalation in patients admitted to the ICU with severe sepsis or septic shock …
of antibiotic de-escalation in patients admitted to the ICU with severe sepsis or septic shock …
Value of lower respiratory tract surveillance cultures to predict bacterial pathogens in ventilator-associated pneumonia: systematic review and diagnostic test accuracy …
N Brusselaers, S Labeau, D Vogelaers, S Blot - Intensive care medicine, 2013 - Springer
Purpose In ventilator-associated pneumonia (VAP), early appropriate antimicrobial therapy
may be hampered by involvement of multidrug-resistant (MDR) pathogens. Methods A …
may be hampered by involvement of multidrug-resistant (MDR) pathogens. Methods A …
Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study
Purpose The recent increase in drug-resistant micro-organisms complicates the
management of hospital-acquired bloodstream infections (HA-BSIs). We investigated the …
management of hospital-acquired bloodstream infections (HA-BSIs). We investigated the …
Procalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. A randomized controlled trial
Y Shehabi, M Sterba, PM Garrett… - American journal of …, 2014 - atsjournals.org
Rationale: The role of procalcitonin (PCT), a widely used sepsis biomarker, in critically ill
patients with sepsis is undetermined. Objectives: To investigate the effect of a low PCT cut …
patients with sepsis is undetermined. Objectives: To investigate the effect of a low PCT cut …
Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients
Objective: We investigated the epidemiology of ventilator-associated pneumonia in elderly
ICU patients. More precisely, we assessed prevalence, risk factors, signs and symptoms …
ICU patients. More precisely, we assessed prevalence, risk factors, signs and symptoms …
Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis
Purpose To describe data on epidemiology, microbiology, clinical characteristics and
outcome of adult patients admitted in the intensive care unit (ICU) with secondary peritonitis …
outcome of adult patients admitted in the intensive care unit (ICU) with secondary peritonitis …
Epidemiology of intra-abdominal infection and sepsis in critically ill patients:“AbSeS”, a multinational observational cohort study and ESICM Trials Group Project
S Blot, M Antonelli, K Arvaniti, K Blot… - Intensive care …, 2019 - Springer
Purpose To describe the epidemiology of intra-abdominal infection in an international cohort
of ICU patients according to a new system that classifies cases according to setting of …
of ICU patients according to a new system that classifies cases according to setting of …
Personalized antibiograms for machine learning driven antibiotic selection
Abstract Background The Centers for Disease Control and Prevention identify antibiotic
prescribing stewardship as the most important action to combat increasing antibiotic …
prescribing stewardship as the most important action to combat increasing antibiotic …