Principles of vaccine design—lessons from nature
F Zepp - Vaccine, 2010 - Elsevier
Microbial pathogens have developed complex and efficient ways of counteracting and
evading innate and adaptive immune mechanisms. The strategies used by pathogens …
evading innate and adaptive immune mechanisms. The strategies used by pathogens …
Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses
Differentiation of naïve B cells, including immunoglobulin class-switch DNA recombination,
is critical for the immune response and depends on the extensive integration of signals from …
is critical for the immune response and depends on the extensive integration of signals from …
Structural roles of PCV2 capsid protein N-terminus in PCV2 particle assembly and identification of PCV2 type-specific neutralizing epitope
X Mo, X Li, B Yin, J Deng, K Tian, A Yuan - PLoS pathogens, 2019 - journals.plos.org
Postweaning multisystemic wasting disease (PMWS) in piglets caused by porcine circovirus
type 2 (PCV2) is one of the major threats to most pig farms worldwide. Among all the PCV …
type 2 (PCV2) is one of the major threats to most pig farms worldwide. Among all the PCV …
A formalin-inactivated vaccine provides good protection against Vibrio harveyi infection in orange-spotted grouper (Epinephelus coioides)
Vibrio harveyi is one of the most common threats to farmed grouper, so considerable efforts
are in practice to control the pathogen. This study presents a highly effective vaccine against …
are in practice to control the pathogen. This study presents a highly effective vaccine against …
Identification of immunodominant T-cell epitopes present in glycoprotein 5 of the North American genotype of porcine reproductive and respiratory syndrome virus
K Vashisht, TL Goldberg, RJ Husmann, W Schnitzlein… - Vaccine, 2008 - Elsevier
Ninty-six pentadecapeptides spanning glycoprotein 5 (GP5) of porcine reproductive and
respiratory virus (PRRSV) were screened for their ability to elicit a recall interferon-γ …
respiratory virus (PRRSV) were screened for their ability to elicit a recall interferon-γ …
Screening of 71 P. multocida Proteins for Protective Efficacy in a Fowl Cholera Infection Model and Characterization of the Protective Antigen PlpE
Background There is a strong need for a recombinant subunit vaccine against fowl cholera.
We used a reverse vaccinology approach to identify putative secreted or cell surface …
We used a reverse vaccinology approach to identify putative secreted or cell surface …
Regulated Delayed Expression of rfaH in an Attenuated Salmonellaenterica Serovar Typhimurium Vaccine Enhances Immunogenicity of Outer Membrane Proteins …
Q Kong, Q Liu, KL Roland, R Curtiss III - Infection and immunity, 2009 - Am Soc Microbiol
RfaH is a transcriptional antiterminator that reduces the polarity of long operons encoding
secreted and surface-associated cell components of Salmonella enterica serovar …
secreted and surface-associated cell components of Salmonella enterica serovar …
[HTML][HTML] An in silico Design, Expression and Purification of a Chimeric Protein as an Immunogen Candidate Consisting of IpaD, StxB, and TolC Proteins from Shigella …
J Fathi, S Nazarian, E Kordbacheh… - Avicenna Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Shigella spp. is the cause of dysentery and is widespread worldwide. On the
other hand, antibiotic resistance is increasing in this bacterium. Bioinformatics is a new …
other hand, antibiotic resistance is increasing in this bacterium. Bioinformatics is a new …
Regulated delayed expression of rfc enhances the immunogenicity and protective efficacy of a heterologous antigen delivered by live attenuated Salmonella enterica …
Q Kong, Q Liu, AM Jansen, R Curtiss III - Vaccine, 2010 - Elsevier
The Salmonella rfc gene encodes the O-antigen polymerase. We constructed three strains in
which we replaced the native rfc promoter with the arabinose-dependent araC PBAD …
which we replaced the native rfc promoter with the arabinose-dependent araC PBAD …
Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice
Background Tuberculosis is one of the most common and deadliest infectious diseases
worldwide affecting almost a third of the world's population. Although this disease is being …
worldwide affecting almost a third of the world's population. Although this disease is being …