Sample preparation is widely accepted as the most labor-intensive and error-prone part of
the bioanalytical process. The recent advances in this field have been focused on the …

The current studies entail Quality by Design (QbD)-enabled development of a simple, rapid,
sensitive and cost-effective high-performance liquid chromatographic method for estimation …

Background Acute kidney injury (AKI), characterised by excessive inflammatory cell
recruitment and programmed cell death, has a high morbidity and mortality; however …

In an acidic buffered solution, erythrosine B can react with amiodarone to form an
association complex, which not only generates great enhancement in resonance Rayleigh …

Amiodarone, a drug associated with significant cardiac, pulmonary, hepatic, and
neurological complications, requires accurate measurement due to its narrow therapeutic …

The aim of this study was to assess the impact of suspended drug by tablet crushing in our
pediatric hospital in term of targeted dose and to identify parameters involved in the potential …

Amiodarone (AM) is the most effective antiarrhythmic agent currently available. However,
clinical application of AM is limited by its serious toxic adverse effects including optic …

Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia. Although
treatment options for AF exist, many patients cannot be maintained in normal sinus rhythm …

Two optimized and validated spectrophotometric methods have been developed for the
determination of amiodarone hydrochloride in commercial dosage forms. Method A is based …

Background and Purpose Amiodarone is one of the most effective anti‐arrhythmic drugs
available, but its clinical applications are limited by toxic side effects including optic toxicity …