Traumatic brain injury (TBI) is a major health and socioeconomic problem that affects all
societies. In recent years, patterns of injury have been changing, with more injuries …

The magnitude of damage to cerebral tissues following head trauma is determined by the
primary injury, caused by the kinetic energy delivered at the time of impact, plus numerous …

Background Tranexamic acid reduces surgical bleeding and decreases mortality in patients
with traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain …

Objectives: Coagulopathy following major trauma is conventionally attributed to activation
and consumption of coagulation factors. Recent studies have identified an acute …

Background CT is the most common imaging modality in traumatic brain injury (TBI).
However, its conventional use requires expert clinical interpretation and does not provide …

Completely updated edition, written by a close-knit author team Presents a unique approach
to stroke-integrated clinical management that weaves together causation, presentation …

Decompressive craniectomy is widely used to treat intracranial hypertension following
traumatic brain injury (TBI). Two randomized trials are currently underway to further evaluate …

In this article, we review past and current experience in clinical trials of traumatic brain
injuries (TBIs), we discuss limitations and challenges, and we summarize current directions …

Traumatic brain injury has long been associated with abnormal coagulation parameters, but
the exact mechanisms underlying this phenomenon are poorly understood. Coagulopathy …

OBJECTIVE: To characterize the natural course of traumatic intraparenchymal contusions
and hematomas (IPHs) and to identify risk factors for IPH progression in the acute post-injury …