Background Post-polio syndrome (PPS) has been traditionally considered a slowly
progressive condition that affects poliomyelitis survivors decades after their initial infection …

A standardised, single-centre, longitudinal imaging protocol was used to evaluate
longitudinal brainstem alterations in 100 patients with amyotrophic lateral sclerosis (ALS) …

Studies suggest that amyotrophic lateral sclerosis (ALS) compromises the integrity of white
matter fiber tracts, primarily affecting motor fibers. However, it remains uncertain whether the …

Background: The cerebellum integrates a multitude of motor and cognitive processes
through ample spinal and supratentorial projections. Despite emerging evidence of adaptive …

Background There is a paucity of cerebral neuroimaging studies in post-polio syndrome
(PPS), despite the severity of neurological and neuropsychological sequelae associated …

Primary lateral sclerosis (PLS) is an adult-onset upper motor neuron disease manifesting in
progressive spasticity and gradually resulting in considerably motor disability. In the …

In the last few years, our understanding of disease molecular mechanisms underpinning
ALS has advanced greatly, allowing the first steps in translating into clinical practice novel …

Background Primary lateral sclerosis (PLS) is traditionally regarded as a pure upper motor
neuron disorder, but recent cases series have highlighted cognitive deficits in executive and …

Introduction Primary lateral sclerosis (PLS) is a rare, adult-onset and slowly progressive
motor neuron disorder whose clinical core is characterized by upper motor neuron (UMN) …

Background Language deficits are cardinal manifestations of some frontotemporal dementia
(FTD) phenotypes and also increasingly recognized in sporadic and familial amyotrophic …