Osteogenesis imperfecta is a genetic disorder of increased bone fragility, low bone mass,
and other connective-tissue manifestations. The most frequently used classification outlines …

The processes of bone growth, modeling, and remodeling determine the structure, mass,
and biomechanical properties of the skeleton. Dysregulated bone resorption or bone …

The major clinical feature that defines osteogenesis imperfecta (OI) is bone fragility. We
begin the chapter with a discussion of the history, prevalence, and classification of OI. After a …

Publisher Summary Osteogenesis imperfecta (OI) or “brittle bone disease” is characterized
by reduced skeletal mass and bone fragility. OI has served as the paradigm for heritable …

Osteogenesis imperfecta (OI) is the most common bone genetic disorder and it is
characterized by bone brittleness and various degrees of growth disorder. Clinical severity …

Several genetic disorders affecting bone mineralization may manifest during dentin
mineralization. Dentin and bone are similar in several aspects, especially pertaining to the …

On the occasion of the 13th International Conference on Osteogenesis imperfecta in August
2017 an expert panel was convened to develop an international consensus paper regarding …

The aim of this investigation was to study dental aberrations in a large sample of unrelated
patients with different types and forms of osteogenesis imperfecta (OI). Sixty-eight non …

Osteogenesis imperfecta is a heritable disorder of bone formation resulting in low bone
mass and a propensity to fracture. It exhibits a broad range of clinical severity, ranging from …

Background: Patients with osteogenesis imperfecta (OI) have significant burden of both
fractures and bony deformities. The present approach to care in this disorder is a …