Mitochondria are cellular organelles responsible for generation of chemical energy in the
process called oxidative phosphorylation. They originate from a bacterial ancestor and …

Abstract In recent years, 5-methylcytosine (m5C) RNA modification has emerged as a key
player in regulating RNA metabolism and function through coding as well as non-coding …

Mitochondria are one of the most important organelles in cells. Mitochondria are semi-
autonomous organelles with their own genetic system, and can independently replicate …

Ribosome biogenesis requires auxiliary factors to promote folding and assembly of
ribosomal proteins and RNA. Particularly, maturation of the peptidyl transferase center (PTC) …

The mitochondrial ribosome (mitoribosome) is a multicomponent machine that has unique
structural features. Biogenesis of the human mitoribosome includes correct maturation and …

Mitochondria control life and death in eukaryotic cells. Harboring a unique circular genome,
a by‐product of an ancient endosymbiotic event, mitochondria maintains a specialized and …

Modified nucleotides in tRNAs are important determinants of folding, structure and function.
Here we identify METTL8 as a mitochondrial matrix protein and active RNA …

Mitochondrial ribosomes (mitoribosomes) synthesize a critical set of proteins essential for
oxidative phosphorylation. Therefore, mitoribosomal function is vital to the cellular energy …

Mammalian mitochondrial ribosomes (mitoribosomes) synthesize a small subset of proteins,
which are essential components of the oxidative phosphorylation machinery. Therefore, their …

Translation termination requires release factors that read a STOP codon in the decoding
center and subsequently facilitate the hydrolysis of the nascent peptide chain from the …