Chemical roots of biological evolution: the origins of life as a process of development of autonomous functional systems
K Ruiz-Mirazo, C Briones… - Open biology, 2017 - royalsocietypublishing.org
In recent years, an extension of the Darwinian framework is being considered for the study of
prebiotic chemical evolution, shifting the attention from homogeneous populations of naked …
prebiotic chemical evolution, shifting the attention from homogeneous populations of naked …
The origin of life: what we know, what we can know and what we will never know
The origin of life (OOL) problem remains one of the more challenging scientific questions of
all time. In this essay, we propose that following recent experimental and theoretical …
all time. In this essay, we propose that following recent experimental and theoretical …
A simple synthetic replicator amplifies itself from a dynamic reagent pool
JW Sadownik, D Philp - … Chemie-International Edition, 2008 - scholars.northwestern.edu
Abstract (Figure Presented) The fate of a dynamic combinatorial library is determined by
coupling the exchange processes to a synthetic replicator. The replicating template is …
coupling the exchange processes to a synthetic replicator. The replicating template is …
Exploring the emergence of complexity using synthetic replicators
T Kosikova, D Philp - Chemical Society Reviews, 2017 - pubs.rsc.org
A significant number of synthetic systems capable of replicating themselves or entities that
are complementary to themselves have appeared in the last 30 years. Building on an …
are complementary to themselves have appeared in the last 30 years. Building on an …
Uncovering the selection criteria for the emergence of multi-building-block replicators from dynamic combinatorial libraries
M Malakoutikhah, JJP Peyralans… - Journal of the …, 2013 - ACS Publications
A family of self-replicating macrocycles was developed using dynamic combinatorial
chemistry. Replication is driven by self-assembly of the replicators into fibrils and relies …
chemistry. Replication is driven by self-assembly of the replicators into fibrils and relies …
Welcome home, systems chemists!
G von Kiedrowski, S Otto, P Herdewijn - Journal of Systems Chemistry, 2010 - Springer
It is our utmost pleasure to launch the Journal of Systems Chemistry. What systems
chemistry exactly is will be known in a few years from now when one is able to sketch the …
chemistry exactly is will be known in a few years from now when one is able to sketch the …
Transient fibril structures facilitating nonenzymatic self-replication
An emerging new direction of research focuses on developing “self-synthesizing materials”,
those supramolecular structures that can promote their own formation by accelerating the …
those supramolecular structures that can promote their own formation by accelerating the …
A dynamic covalent, luminescent metallopolymer that undergoes sol-to-gel transition on temperature rise
The condensation of linear diamine and dialdehyde subcomponents around copper (I)
templates in the presence of bulky trioctylphosphine ancillary ligands gave a linear …
templates in the presence of bulky trioctylphosphine ancillary ligands gave a linear …
Primitive selection of the fittest emerging through functional synergy in nucleopeptide networks
AK Bandela, N Wagner, H Sadihov… - Proceedings of the …, 2021 - National Acad Sciences
Many fundamental cellular and viral functions, including replication and translation, involve
complex ensembles hosting synergistic activity between nucleic acids and …
complex ensembles hosting synergistic activity between nucleic acids and …
Artificial Homeostasis Systems Based on Feedback Reaction Networks: Design Principles and Future Promises
VA Ranganath, I Maity - Angewandte Chemie International …, 2024 - Wiley Online Library
Feedback‐controlled chemical reaction networks (FCRNs) are indispensable for various
biological processes, such as cellular mechanisms, patterns, and signaling pathways …
biological processes, such as cellular mechanisms, patterns, and signaling pathways …