Post-acute COVID-19 sequelae, commonly known as long COVID, encompasses a range of
systemic symptoms experienced by a significant number of COVID-19 survivors. The …

The limitation of cancer radiotherapy does not derive from an inability to ablate tumor, but
rather to do so without excessively damaging critical tissues and organs and adversely …

Immunotherapies that produce durable responses in some malignancies have failed in
pancreatic ductal adenocarcinoma (PDAC) due to rampant immune suppression and poor …

The cyclic GMP–AMP synthase–stimulator of interferon genes (cGAS–STING) pathway is an
essential component of the innate immune system and is central to the identification of …

Introduction Glioma is the most common primary brain tumor and is often associated with
treatment resistance and poor prognosis. Standard treatment typically involves radiotherapy …

Early and accurate diagnosis and treatment of pancreatic cancer (PC) remain challenging
endeavors globally. Late diagnosis lag, high invasiveness, chemical resistance, and poor …

CD1d-restricted invariant natural killer T (iNKT) cells actively patrol the liver and possess
valuable antitumor potential. However, clinical trials evaluating administration of iNKT cell …

Accumulating evidence has suggested the impact of senescence on tumor progression, but
no report has yet described how senescence shapes the tumor microenvironment of clear …

With the high morbidity and mortality, hepatocellular carcinoma (HCC) represents a major
yet growing burden for our global community. The relapse-prone nature and drug resistance …

Cancer progression is continuously controlled by the immune system which can identify and
destroy nascent tumor cells or inhibit metastatic spreading. However, the immune system …