Neuroinflammation and scarring after spinal cord injury: therapeutic roles of MSCs on inflammation and glial scar

QM Pang, SY Chen, QJ Xu, SP Fu, YC Yang… - Frontiers in …, 2021 - frontiersin.org
Transected axons are unable to regenerate after spinal cord injury (SCI). Glial scar is
thought to be responsible for this failure. Regulating the formation of glial scar post-SCI may …

[HTML][HTML] New insights into peripheral nerve regeneration: The role of secretomes

E Contreras, S Bolívar, X Navarro, E Udina - Experimental Neurology, 2022 - Elsevier
Neurons of the peripheral nervous system retain the intrinsic capability of regenerate their
axons after injury, by triggering a complex activation response. This genetic switch is …

Regulatory role of mesenchymal stem cells on secondary inflammation in spinal cord injury

QM Pang, SY Chen, SP Fu, H Zhou… - Journal of …, 2022 - Taylor & Francis
Spinal cord injury (SCI) is a catastrophic condition with high morbidity and mortality that still
lacks effective therapeutic strategies. It is well known that the most important stage in SCI …

Mesenchymal stem cell-derived exosomes ameliorate diabetic kidney disease through the NLRP3 signaling pathway

Y Wang, J Liu, H Wang, S Lv, Q Liu, S Li, X Yang… - Stem Cells, 2023 - academic.oup.com
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease worldwide.
Exosomes (Exo) derived from human umbilical cord mesenchymal stem cells (HUC-MSCs) …

Neural cells for neurodegenerative diseases in clinical trials

Y Fan, ELK Goh, JKY Chan - Stem Cells Translational Medicine, 2023 - academic.oup.com
Neurodegenerative diseases (ND) are an entire spectrum of clinical conditions that affect the
central and peripheral nervous system. There is no cure currently, with treatment focusing …

ACSL4-Mediated ferroptosis and its potential role in central nervous system diseases and injuries

B Jia, J Li, Y Song, C Luo - International Journal of Molecular Sciences, 2023 - mdpi.com
As an iron-dependent regulated form of cell death, ferroptosis is characterized by iron-
dependent lipid peroxidation and has been implicated in the occurrence and development …

[HTML][HTML] Mesenchymal stem cell therapy in amyotrophic lateral sclerosis (ALS) patients: A comprehensive review of disease information and future perspectives

S Najafi, P Najafi, NK Farkhad, GH Torshizi… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a rare deadly progressive neurological disease that
primarily affects the upper and lower motor neurons with an annual incidence rate of 0.6 to …

[HTML][HTML] Advanced approaches to regenerate spinal cord injury: The development of cell and tissue engineering therapy and combinational treatments

J Saremi, N Mahmoodi, M Rasouli, FE Ranjbar… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …

[Retracted] Recent Advances in Cell and Functional Biomaterial Treatment for Spinal Cord Injury

T Liu, W Zhu, X Zhang, C He, X Liu… - BioMed Research …, 2022 - Wiley Online Library
Spinal cord injury (SCI) is a devastating central nervous system disease caused by
accidental events, resulting in loss of sensory and motor function. Considering the multiple …

Application of mesenchymal stem cells (MSCs) in neurodegenerative disorders: history, findings, and prospective challenges

N Biglari, A Mehdizadeh, MV Mastanabad… - … -Research and Practice, 2023 - Elsevier
Over the past few decades, the application of mesenchymal stem cells has captured the
attention of researchers and practitioners worldwide. These cells can be obtained from …