Schistosomiasis is an infectious disease caused by helminth parasites of the genus
Schistosoma. Worldwide, an estimated 250 million people are infected with these parasites …

Background Historically, the target in the schistosomiasis control has shifted from infection to
morbidity, then back to infection, but now as a public health problem, before moving on to …

Schistosomiasis treatment relies on the use of a single drug, praziquantel, which is
insufficient to control transmission in highly endemic areas. Novel medicines and vaccines …

Drug discovery for schistosomiasis is still limited to a handful of academic laboratories
worldwide, with only a few novel antischistosomal lead compounds being actively …

The anthelmintic drug praziquantel (PZQ) is used to treat schistosomiasis, a neglected
tropical disease that affects over 200 million people worldwide. PZQ causes Ca 2+ influx …

Control strategies to reduce human schistosomiasis have evolved from 'snail
picking'campaigns, a century ago, to modern wide-scale human treatment campaigns, or …

Infections caused by parasitic flatworms impose a considerable worldwide health burden.
One of the most impactful is schistosomiasis, a disease caused by parasitic blood flukes …

Porcine cysticercosis, human taeniasis, and (neuro) cysticercosis are endemic in many low-
and middle-income countries (LMIC) where they present a significant health burden to …

Schistosomiasis treatment entirely relies on a single drug, praziquantel, prompting research
into alternative therapeutics. Here we evaluated the efficacy and safety of the antimalarial …

Schistosomiasis, a severe parasitic disease, is primarily caused by Schistosoma mansoni,
Schistosoma japonicum, or Schistosoma haematobium. Currently, praziquantel is the only …