The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

Allergic asthma is associated with airway inflammation and airway hyperresponsiveness.
Macrophage polarization has been shown to have a profound impact on asthma …

Macrophages are the most numerous immune-cells present in the lung environment under
homoeostatic conditions and are ideally positioned to dictate the innate defence of the …

Macrophages are strategically located throughout the body tissues, where they ingest and
process foreign materials, dead cells and debris and recruit additional macrophages in …

Fine control of macrophage activation is needed to prevent inflammatory disease,
particularly at barrier sites such as the lungs. However, the dominant mechanisms that …

The classical view of the Th1/Th2 paradigm posits that the pathogen nature, infectious cycle,
and persistence represent key parameters controlling the choice of effector mechanisms …

Background Emerging evidence indicates that, similarly to what happens for peripheral
macrophages, microglia can express different phenotypes depending on …

The lung is highly exposed to the external environment. For this reason, the lung needs to
handle a number of potential threats present in inhaled air such as viruses or bacteria …

Although alveolar macrophages (AMs) from patients with asthma are known to be
functionally different from those of healthy individuals, the mechanism by which this …

Lung macrophages link innate and adaptive immune responses during allergic airway
inflammatory responses. Alveolar macrophages (AMs) and interstitial macrophages are two …