Antimicrobial resistance, mechanisms and its clinical significance

MA Abushaheen, AJ Fatani, M Alosaimi, W Mansy… - Disease-a-Month, 2020 - Elsevier
Antimicrobial agents play a key role in controlling and curing infectious disease. Soon after
the discovery of the first antibiotic, the challenge of antibiotic resistance commenced …

Plasmid transfer by conjugation in Gram-negative bacteria: from the cellular to the community level

C Virolle, K Goldlust, S Djermoun, S Bigot, C Lesterlin - Genes, 2020 - mdpi.com
Bacterial conjugation, also referred to as bacterial sex, is a major horizontal gene transfer
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …

Type IV secretion systems: advances in structure, function, and activation

TRD Costa, L Harb, P Khara, L Zeng, B Hu… - Molecular …, 2021 - Wiley Online Library
Bacterial type IV secretion systems (T4SSs) are a functionally diverse translocation
superfamily. They consist mainly of two large subfamilies:(i) conjugation systems that …

Type IV secretion in Gram‐negative and Gram‐positive bacteria

E Grohmann, PJ Christie, G Waksman… - Molecular …, 2018 - Wiley Online Library
Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …

Integrative and conjugative elements (ICEs): what they do and how they work

CM Johnson, AD Grossman - Annual review of genetics, 2015 - annualreviews.org
Horizontal gene transfer plays a major role in microbial evolution, allowing microbes to
acquire new genes and phenotypes. Integrative and conjugative elements (ICEs, aka …

Horizontal gene transfer in human pathogens

M Juhas - Critical reviews in microbiology, 2015 - Taylor & Francis
Horizontal gene transfer has a tremendous impact on the genome plasticity, adaptation and
evolution of bacteria. Horizontally transferred mobile genetic elements are involved in the …

Transferable Plasmids of Salmonella enterica Associated With Antibiotic Resistance Genes

EA McMillan, CR Jackson, JG Frye - Frontiers in microbiology, 2020 - frontiersin.org
Salmonella enterica is a common foodborne illness in the United States and globally. An
increasing number of Salmonella infections are resistant to antibiotics, and many of the …

F conjugation: back to the beginning

D Arutyunov, LS Frost - Plasmid, 2013 - Elsevier
Bacterial conjugation as mediated by the F plasmid has been a topic of study for the past
65years. Early research focused on events that occur on the cell surface including the pilus …

[HTML][HTML] The expanding bacterial type IV secretion lexicon

M Bhatty, JAL Gomez, PJ Christie - Research in microbiology, 2013 - Elsevier
The bacterial type IV secretion systems (T4SSs) comprise a biologically diverse group of
translocation systems functioning to deliver DNA or protein substrates from donor to target …

[HTML][HTML] Secrete or perish: the role of secretion systems in Xanthomonas biology

CE Alvarez-Martinez, GG Sgro, GG Araujo… - Computational and …, 2021 - Elsevier
Bacteria of the Xanthomonas genus are mainly phytopathogens of a large variety of crops of
economic importance worldwide. Xanthomonas spp. rely on an arsenal of protein effectors …