Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific
biological information and have progressively emerged as key regulators of organized …

The WNT signaling pathways are major regulators of organ development. Ample research
over the past few decades revealed that these pathways are critically involved in adult tissue …

Aims/hypothesis Diabetic peripheral neuropathy (DPN) is one of the major complications of
diabetes, which contributes greatly to morbidity and mortality. There is currently no effective …

Exosome is a nanoscale vesicle with a size range of 30–100 nm. It is secreted from cell to
extracellular space by exocytosis after fusion of multivesicular body (MVB)(formed by …

Diabetic nephropathy (DN) is a major microvascular complication of diabetes mellitus. It is
the most frequent cause of end-stage renal disease with no definitive therapy available so …

Background Diabetic nephropathy (DN) is an increasing threat to human health and
regarded to be the leading cause of end-stage renal disease worldwide. Exosomes delivery …

Diabetic nephropathy (DN) is one of the major microvascular complications of diabetes
mellitus and the leading cause of end-stage kidney disease. The standard treatments for …

Type 2 diabetes mellitus (T2DM), a chronic disease, is widely prevalent all over the world. In
recent years, the roles of some extracellular vesicles (EVs) in T2DM have attracted much …

Diabetic kidney disease (DKD) is closely associated with the high risk of cardiovascular
disease and mortality. Exosomal circRNAs can exert significant roles in the pathology of …

Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles,
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …